IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i12p7355-d839614.html
   My bibliography  Save this article

Application of Place-Based Methods to Lung Transplant Medicine

Author

Listed:
  • Wayne M. Tsuang

    (Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA)

  • Maeve MacMurdo

    (Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA)

  • Jacqueline Curtis

    (GIS Health & Hazards Lab, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA)

Abstract

Lung transplantation is an increasingly common lifesaving therapy for patients with fatal lung diseases, but this intervention has a critical limitation as median survival after LT is merely 5.5 years. Despite the profound impact of place-based factors on lung health, this has not been rigorously investigated in LT recipients—a vulnerable population due to the lifelong need for daily life-sustaining immunosuppression medications. There have also been longstanding methodological gaps in transplant medicine where both time and place have not been measured; gaps which could be filled by the geospatial sciences. As part of an exploratory analysis, we studied recipients transplanted at our center over a two-year period. The main outcome was at least one episode of rejection within the first year after transplant. We found recipients averaged 1.7 unique residential addresses, a modest relocation rate. Lung rejection was associated with census tracts of predominantly underrepresented minorities or where English was not the primary language as measured by the social vulnerability index. Census tracts likely play an important role in measuring and addressing geographic disparities in transplantation. In a future paradigm, patient spatial data could become an integrated part of real time clinical care to aid in personalized risk stratification and personalized delivery of healthcare.

Suggested Citation

  • Wayne M. Tsuang & Maeve MacMurdo & Jacqueline Curtis, 2022. "Application of Place-Based Methods to Lung Transplant Medicine," IJERPH, MDPI, vol. 19(12), pages 1-9, June.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:12:p:7355-:d:839614
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/12/7355/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/12/7355/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Flowerdew, Robin & Manley, David J. & Sabel, Clive E., 2008. "Neighbourhood effects on health: Does it matter where you draw the boundaries?," Social Science & Medicine, Elsevier, vol. 66(6), pages 1241-1255, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Eleonore M Veldhuizen & Karien Stronks & Anton E Kunst, 2013. "Assessing Associations between Socio-Economic Environment and Self-Reported Health in Amsterdam Using Bespoke Environments," PLOS ONE, Public Library of Science, vol. 8(7), pages 1-10, July.
    2. Martin Gaechter & Peter Schwazer & Engelbert Theurl, 2012. "Stronger Sex but Earlier Death: A Multi-level Socioeconomic Analysis of Gender Differences in Mortality in Austria," DANUBE: Law and Economics Review, European Association Comenius - EACO, issue 1, pages 1-23, March.
    3. Hamidreza Rabiei‐Dastjerdi & Stephen A. Matthews, 2021. "Who gets what, where, and how much? Composite index of spatial inequality for small areas in Tehran," Regional Science Policy & Practice, Wiley Blackwell, vol. 13(1), pages 191-205, February.
    4. Christoph Lambio & Tillman Schmitz & Richard Elson & Jeffrey Butler & Alexandra Roth & Silke Feller & Nicolai Savaskan & Tobia Lakes, 2023. "Exploring the Spatial Relative Risk of COVID-19 in Berlin-Neukölln," IJERPH, MDPI, vol. 20(10), pages 1-22, May.
    5. Danny Wende, 2019. "Spatial risk adjustment between health insurances: using GWR in risk adjustment models to conserve incentives for service optimisation and reduce MAUP," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 20(7), pages 1079-1091, September.
    6. Samantha Cockings & Andrew Harfoot & David Martin & Duncan Hornby, 2013. "Getting the Foundations Right: Spatial Building Blocks for Official Population Statistics," Environment and Planning A, , vol. 45(6), pages 1403-1420, June.
    7. Anthony Buttaro & Ludovica Gambaro & Heather Joshi & Mary Clare Lennon, 2021. "Neighborhood and Child Development at Age Five: A UK–US Comparison," IJERPH, MDPI, vol. 18(19), pages 1-16, October.
    8. Stephen Matthews & Daniel M. Parker, 2013. "Progress in Spatial Demography," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 28(10), pages 271-312.
    9. Hongwei Xu & John Logan & Susan Short, 2014. "Integrating Space With Place in Health Research: A Multilevel Spatial Investigation Using Child Mortality in 1880 Newark, New Jersey," Demography, Springer;Population Association of America (PAA), vol. 51(3), pages 811-834, June.
    10. Chunzhu Wei & Pablo Cabrera-Barona & Thomas Blaschke, 2016. "Local Geographic Variation of Public Services Inequality: Does the Neighborhood Scale Matter?," IJERPH, MDPI, vol. 13(10), pages 1-20, October.
    11. Samantha Cockings & Andrew Harfoot & David Martin & Duncan Hornby, 2011. "Maintaining Existing Zoning Systems Using Automated Zone-Design Techniques: Methods for Creating the 2011 Census Output Geographies for England and Wales," Environment and Planning A, , vol. 43(10), pages 2399-2418, October.
    12. Lauren P. Grant & Chris Gennings & Edmond P. Wickham & Derek Chapman & Shumei Sun & David C. Wheeler, 2018. "Modeling Pediatric Body Mass Index and Neighborhood Environment at Different Spatial Scales," IJERPH, MDPI, vol. 15(3), pages 1-19, March.
    13. Hirsch, Jana A. & Grengs, Joe & Schulz, Amy & Adar, Sara D. & Rodriguez, Daniel A. & Brines, Shannon J. & Diez Roux, Ana V., 2016. "How much are built environments changing, and where?: Patterns of change by neighborhood sociodemographic characteristics across seven U.S. metropolitan areas," Social Science & Medicine, Elsevier, vol. 169(C), pages 97-105.
    14. Castelli, Adriana & Jacobs, Rowena & Goddard, Maria & Smith, Peter C., 2013. "Health, policy and geography: Insights from a multi-level modelling approach," Social Science & Medicine, Elsevier, vol. 92(C), pages 61-73.
    15. Thomas C. McHale & Claudia M. Romero-Vivas & Claudio Fronterre & Pedro Arango-Padilla & Naomi R. Waterlow & Chad D. Nix & Andrew K. Falconar & Jorge Cano, 2019. "Spatiotemporal Heterogeneity in the Distribution of Chikungunya and Zika Virus Case Incidences during their 2014 to 2016 Epidemics in Barranquilla, Colombia," IJERPH, MDPI, vol. 16(10), pages 1-21, May.
    16. Katherine E. King, 2015. "A Comparison of Two Methods for Measuring Land Use in Public Health Research," SAGE Open, , vol. 5(2), pages 21582440155, June.
    17. Scott Orford & Charlotte Leigh, 2014. "The Relationship between Self-reported Definitions of Urban Neighbourhood and Respondent Characteristics: A Study of Cardiff, UK," Urban Studies, Urban Studies Journal Limited, vol. 51(9), pages 1891-1908, July.
    18. Root, Elisabeth Dowling & Humphrey, Jamie L., 2014. "Neighborhood racial composition and trajectories of child self-rated health: An application of longitudinal propensity scores," Social Science & Medicine, Elsevier, vol. 120(C), pages 31-39.
    19. Ross W. Fineman, 2020. "The Shortest Path Isolation Index: A New Measure for Individual-level Residential Segregation," Sociological Methods & Research, , vol. 49(3), pages 742-777, August.
    20. Rainham, Daniel & McDowell, Ian & Krewski, Daniel & Sawada, Mike, 2010. "Conceptualizing the healthscape: Contributions of time geography, location technologies and spatial ecology to place and health research," Social Science & Medicine, Elsevier, vol. 70(5), pages 668-676, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:12:p:7355-:d:839614. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.