IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i5p2652-d511745.html
   My bibliography  Save this article

Trace Element Analysis in Whole Blood and Plasma for Reference Levels in a Selected Queensland Population, Australia

Author

Listed:
  • Tatiana Komarova

    (Queensland Health Forensic and Scientific Services, Coopers Plains, QLD 4108, Australia)

  • Daniel McKeating

    (School of Medical Sciences, Griffith University, Parklands Drive, Southport, Gold Coast, QLD 4222, Australia)

  • Anthony V. Perkins

    (School of Medical Sciences, Griffith University, Parklands Drive, Southport, Gold Coast, QLD 4222, Australia)

  • Ujang Tinggi

    (Queensland Health Forensic and Scientific Services, Coopers Plains, QLD 4108, Australia)

Abstract

The levels of trace elements in whole blood and plasma have been widely used for assessing nutritional status and monitoring exposure and can vary widely in populations from different geographical regions. In this study, whole blood samples ( n = 120) and plasma samples ( n = 120) were obtained from healthy donors attending the Red Cross Blood Bank (Queensland Red Cross Blood Service), which provided information for age and sex. There were 71 males (age range: 19–73 years) and 49 females (age range: 18–72 years) for whole blood samples, and 59 males (age range: 19–81 years) and 61 females (age range: 19–73 years) for plasma samples. The main aim of the study was to provide information on blood reference levels of 21 trace elements (Ag, Al, As, Bi, Br, Cd, Co, Cr, Cu, Hg, I, Mn, Mo, Ni, Pb, Sb, Se, Tl, U, V, Zn) in Queensland. The study also aimed to assess differences in trace element blood levels between males and females and the effect of age. The trace element levels in blood samples were analysed using inductively coupled plasma mass spectrometry (ICP-MS) and the standard reference materials of Seronorm (Trace Elements Whole Blood) and UTAK (Trace Elements Serum) were used for quality control and assurance. The study found wide variations of trace element levels in whole blood and plasma, and generally the levels were comparable to other countries. No detectable levels were found for Bi, Cr, U and V in whole blood, but V levels were found in plasma samples. There were significant differences between males and females for whole blood Cu ( p < 0.001), I ( p = 0.009), Tl ( p = 0.016) and Zn ( p = 0.016). Significant differences were also found for plasma Cu ( p < 0.001) and Se ( p = 0.003) between males and females. There were trends of increased levels of blood Pb, Se and Zn with age. The study has provided further information on a wide range of trace elements in blood as reference levels for Queensland and Australia which are currently lacking.

Suggested Citation

  • Tatiana Komarova & Daniel McKeating & Anthony V. Perkins & Ujang Tinggi, 2021. "Trace Element Analysis in Whole Blood and Plasma for Reference Levels in a Selected Queensland Population, Australia," IJERPH, MDPI, vol. 18(5), pages 1-15, March.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:5:p:2652-:d:511745
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/5/2652/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/5/2652/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Janja Snoj Tratnik & Darja Mazej & Milena Horvat, 2019. "Analytical Quality Requirements in Human Biomonitoring Programs: Trace Elements in Human Blood," IJERPH, MDPI, vol. 16(13), pages 1-16, June.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Yang Cao & Huidi Zhang & Jingxin Yang & Qingqing Man & Pengkun Song & Deqian Mao & Jiaxi Lu & Lichen Yang, 2022. "Reference Ranges of Selenium in Plasma and Whole Blood for Child-Bearing-Aged Women in China," IJERPH, MDPI, vol. 19(8), pages 1-9, April.
    2. Karolina Kot & Natalia Łanocha-Arendarczyk & Patrycja Kupnicka & Sławomir Szymański & Witold Malinowski & Elżbieta Kalisińska & Dariusz Chlubek & Danuta Kosik-Bogacka, 2021. "Selected Metal Concentration in Maternal and Cord Blood," IJERPH, MDPI, vol. 18(23), pages 1-12, November.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:5:p:2652-:d:511745. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.