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The Effect of Lifestyle Intervention on Health-Related Quality of Life in Adults with Metabolic Syndrome: A Meta-Analysis

Author

Listed:
  • Alba Marcos-Delgado

    (Departamento de Ciencias Biomédicas, Área de Medicina Preventiva y Salud Pública, Universidad de León, 24071 León, Spain)

  • Natalia Hernández-Segura

    (Departamento de Ciencias Biomédicas, Área de Medicina Preventiva y Salud Pública, Universidad de León, 24071 León, Spain)

  • Tania Fernández-Villa

    (Departamento de Ciencias Biomédicas, Área de Medicina Preventiva y Salud Pública, Universidad de León, 24071 León, Spain)

  • Antonio J. Molina

    (Departamento de Ciencias Biomédicas, Área de Medicina Preventiva y Salud Pública, Universidad de León, 24071 León, Spain)

  • Vicente Martín

    (Departamento de Ciencias Biomédicas, Área de Medicina Preventiva y Salud Pública, Universidad de León, 24071 León, Spain
    CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, 28029 Madrid, Spain)

Abstract

The aim of this meta-analysis was to assess the effects of a lifestyle intervention through health education on nutrition, physical activity, and healthy habits on physical and mental health-related quality of life (HRQoL), in adults with metabolic syndrome (MetS). The databases used were PubMed, WOS, and Scopus. The inclusion criteria were: observational, longitudinal and randomized clinical trial (RCT) study designs, adults (both sexes), with at least two criteria of MetS, lifestyle intervention and comparison with a control group, and a measurement of HRQoL with a validated questionnaire. We analyzed the Hedges’ g and SF-36 score. I 2 statistics were calculated and possible publication and small study biases were assessed using Egger’s test and funnel plots. Seven RCTs were selected for meta-analysis, based on 637 study participants. Significant improvements were found in the physical dimensions of the HRQoL scores for subjects in the active intervention compared to the group that received general lifestyle information (Hedges’ g 0.61, 95% confidence interval (CI) = 0.31–0.91). Mental health-related quality of life was also significantly improved in the intervention group compared with the control group (Hedges’ g 0.84, 95% CI = 0.64–1.03). In conclusion, our results suggest that, according to the RCTs selected for this meta-analysis, a lifestyle intervention significantly improves HRQoL in all its domains.

Suggested Citation

  • Alba Marcos-Delgado & Natalia Hernández-Segura & Tania Fernández-Villa & Antonio J. Molina & Vicente Martín, 2021. "The Effect of Lifestyle Intervention on Health-Related Quality of Life in Adults with Metabolic Syndrome: A Meta-Analysis," IJERPH, MDPI, vol. 18(3), pages 1-14, January.
  • Handle: RePEc:gam:jijerp:v:18:y:2021:i:3:p:887-:d:484065
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    Citations

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    Cited by:

    1. Rafael Marfil-Carmona & Manuel Ortega-Caballero & Félix Zurita-Ortega & José Luis Ubago-Jiménez & Gabriel González-Valero & Pilar Puertas-Molero, 2021. "Impact of the Mass Media on Adherence to the Mediterranean Diet, Psychological Well-Being and Physical Activity. Structural Equation Analysis," IJERPH, MDPI, vol. 18(7), pages 1-13, April.
    2. José E. Teixeira & José A. Bragada & João P. Bragada & Joana P. Coelho & Isabel G. Pinto & Luís P. Reis & Paula O. Fernandes & Jorge E. Morais & Pedro M. Magalhães, 2022. "Structural Equation Modelling for Predicting the Relative Contribution of Each Component in the Metabolic Syndrome Status Change," IJERPH, MDPI, vol. 19(6), pages 1-14, March.

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