IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i21p11294-d666305.html
   My bibliography  Save this article

Italian Expert Consensus on Clinical and Therapeutic Management of Multiple Chemical Sensitivity (MCS)

Author

Listed:
  • Giovanni Damiani

    (Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy
    Clinical Dermatology, IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy
    PhD Degree Program in Pharmacological Sciences, Department of Pharmaceutical and Pharmacological Sciences, University of Padua, 35131 Padua, Italy)

  • Marco Alessandrini

    (Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, 00133 Rome, Italy)

  • Daniela Caccamo

    (Department of Biomedical Sciences, Dental Sciences, & Morpho-Functional Imaging, Polyclinic Hospital University, 98124 Messina, Italy)

  • Andrea Cormano

    (International Society of Doctors for Environment, 82100 Benevento, Italy)

  • Gianpaolo Guzzi

    (Italian Association for Metals and Biocompatibility Research—A.I.R.M.E.B., 20122 Milan, Italy)

  • Andrea Mazzatenta

    (Department of Neuroscience, Imaging and Clinical Science, ‘G. d’Annunzio’ University of Chieti-Pescara, 66100 Chieti, Italy)

  • Alessandro Micarelli

    (Institute of Mountain Emergency Medicine, Eurac Research, 39100 Bolzano, Italy
    ITER Center for Balance and Rehabilitation Research (ICBRR), 02032 Rome, Italy)

  • Alberto Migliore

    (Department of Internal Medicine, Unit of Rheumatology, San Pietro Fatebenefratelli Hospital, 00189 Rome, Italy)

  • Alba Piroli

    (Department of MeSVA, University of L’Aquila, 67100 L’Aquila, Italy)

  • Margherita Bianca

    (Patient with Multiple Chemical Sensitivity (MCS. The patient wanted to remain anonymous, so we decided to use a pseudonym).)

  • Ottaviano Tapparo

    (Natrail Tagesklinik, 81925 Munchen, Germany)

  • Paolo Daniele Maria Pigatto

    (Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy
    Clinical Dermatology, IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy)

Abstract

Multiple chemical sensitivity (MCS) is a multisystem, recurrent, environmental disorder that flares in response to different exposures (i.e., pesticides, solvents, toxic metals and molds) under the threshold limit value (TLV) calculated for age and gender in the general population. MCS is a syndrome characterized by cutaneous, allergic, gastrointestinal, rheumatological, endocrinological, cardiological and neurological signs and symptoms. We performed a systematic review of the literature to summarize the current clinical and therapeutic evidence and then oriented an eDelphi consensus. Four main research domains were identified (diagnosis, treatment, hospitalization and emergency) and discussed by 10 experts and an MCS patient. Thus, the first Italian MCS consensus had the double aim: (a) to improve MCS knowledge among healthcare workers and patients by standardizing the clinical and therapeutic management to MCS patients; and (b) to improve and shed light on MCS misconceptions not supported by evidence-based medicine (EBM).

Suggested Citation

  • Giovanni Damiani & Marco Alessandrini & Daniela Caccamo & Andrea Cormano & Gianpaolo Guzzi & Andrea Mazzatenta & Alessandro Micarelli & Alberto Migliore & Alba Piroli & Margherita Bianca & Ottaviano T, 2021. "Italian Expert Consensus on Clinical and Therapeutic Management of Multiple Chemical Sensitivity (MCS)," IJERPH, MDPI, vol. 18(21), pages 1-19, October.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:21:p:11294-:d:666305
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/21/11294/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/21/11294/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Anne A. Bjerregaard & Marie W. Petersen & Lise Kirstine Gormsen & Sine Skovbjerg & Niklas R. Jørgensen & Allan Linneberg & José G. Cedeño-Laurent & Torben Jørgensen & Thomas M. Dantoft, 2021. "Insulin Resistance Is Associated with Multiple Chemical Sensitivity in a Danish Population-Based Study—DanFunD," IJERPH, MDPI, vol. 18(23), pages 1-13, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:21:p:11294-:d:666305. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.