IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i15p7996-d603448.html
   My bibliography  Save this article

Association of Short-Term Particulate Matter Exposure among 5-Year Cancer Survivors with Incident Cardiovascular Disease: A Time-Stratified Case-Crossover Study

Author

Listed:
  • Seulggie Choi

    (Department of Biomedical Sciences, Graduate School, Seoul National University, Seoul 03080, Korea)

  • Kyae Hyung Kim

    (Department of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea)

  • Daein Choi

    (Department of Internal Medicine, Mount Sinai Beth Israel, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA)

  • Seogsong Jeong

    (Department of Biomedical Sciences, Graduate School, Seoul National University, Seoul 03080, Korea)

  • Kyuwoong Kim

    (National Cancer Control Institute, National Cancer Center, Goyang 10408, Korea)

  • Jooyoung Chang

    (Department of Biomedical Sciences, Graduate School, Seoul National University, Seoul 03080, Korea)

  • Sung Min Kim

    (Department of Biomedical Sciences, Graduate School, Seoul National University, Seoul 03080, Korea)

  • Seong Rae Kim

    (College of Medicine, Seoul National University Hospital, Seoul 03080, Korea)

  • Yoosun Cho

    (Total Healthcare Center, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul 06351, Korea)

  • Gyeongsil Lee

    (Department of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea)

  • Joung Sik Son

    (Department of Family Medicine, Korea University Guro Hospital, Seoul 08308, Korea)

  • Sang Min Park

    (Department of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea
    Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Korea)

Abstract

The association of short-term particulate matter concentration with cardiovascular disease (CVD) among cancer survivors is yet unclear. Using the National Health Insurance Service database from South Korea, the study population consisted of 22,864 5-year cancer survivors with CVD events during the period 2015–2018. Using a time-stratified case-crossover design, each case date (date of incident CVD) was matched with three or four referent dates, resulting in a total of 101,576 case and referent dates. The daily average particulate matter 10 (PM10), 2.5 (PM2.5), and 2.5–10 (PM2.5–10) on the day of case or referent date (lag0), 1–3 days before the case or referent date (lag1, lag2, and lag3), and the mean value 0–3 days before the case or referent date (lag0–3) were determined. Conditional logistic regression was conducted to calculate the adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for CVD according to quartiles of PM10, PM2.5, and PM2.5–10. Compared to the 1st (lowest) quartile of lag0–3 PM10, the 4th (highest) quartile of lag0–3 PM10 was associated with higher odds for CVD (aOR 1.13, 95% CI 1.06–1.21). The 4th quartiles of lag1 (aOR 1.12, 95% CI 1.06–1.19), lag2 (aOR 1.09, 95% CI 1.03–1.16), lag3 (aOR 1.06, 95% CI 1.00–1.12), and lag0–3 (aOR 1.11, 95% CI 1.05–1.18) PM2.5 were associated with higher odds for CVD compared to the respective 1st quartiles. Similarly, the 4th quartile of lag0–3 PM2.5–10 was associated with higher CVD events (aOR 1.11, 95% CI 1.03–1.19) compared to the 1st quartile. Short-term exposure to high levels of PM may be associated with increased CVD risk among cancer survivors.

Suggested Citation

  • Seulggie Choi & Kyae Hyung Kim & Daein Choi & Seogsong Jeong & Kyuwoong Kim & Jooyoung Chang & Sung Min Kim & Seong Rae Kim & Yoosun Cho & Gyeongsil Lee & Joung Sik Son & Sang Min Park, 2021. "Association of Short-Term Particulate Matter Exposure among 5-Year Cancer Survivors with Incident Cardiovascular Disease: A Time-Stratified Case-Crossover Study," IJERPH, MDPI, vol. 18(15), pages 1-12, July.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:15:p:7996-:d:603448
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/15/7996/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/15/7996/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Seulggie Choi & Kyae Hyung Kim & Kyuwoong Kim & Jooyoung Chang & Sung Min Kim & Seong Rae Kim & Yoosun Cho & Gyeongsil Lee & Joung Sik Son & Sang Min Park, 2020. "Association between Post-Diagnosis Particulate Matter Exposure among 5-Year Cancer Survivors and Cardiovascular Disease Risk in Three Metropolitan Areas from South Korea," IJERPH, MDPI, vol. 17(8), pages 1-12, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Seo Yun Hwang & Seogsong Jeong & Seulggie Choi & Dong Hyun Kim & Seong Rae Kim & Gyeongsil Lee & Joung Sik Son & Sang Min Park, 2021. "Association of Air Pollutants with Incident Chronic Kidney Disease in a Nationally Representative Cohort of Korean Adults," IJERPH, MDPI, vol. 18(7), pages 1-10, April.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:15:p:7996-:d:603448. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.