IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i13p6775-d581057.html
   My bibliography  Save this article

High Risk of Peritonsillar Abscess in End-Stage Renal Disease Patients: A Nationwide Real-World Cohort Study

Author

Listed:
  • Geng-He Chang

    (Department of Otolaryngology—Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan
    Health Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan
    Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan)

  • Ang Lu

    (Department of Otolaryngology—Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan)

  • Yao-Hsu Yang

    (Health Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan
    Department of Traditional Chinese Medicine, Chiayi Branch of Chang-Gung Memorial Hospital, Chiayi 613, Taiwan
    School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan)

  • Chia-Yen Liu

    (Health Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan)

  • Pey-Jium Chang

    (Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan)

  • Chuan-Pin Lee

    (Health Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan)

  • Yao-Te Tsai

    (Department of Otolaryngology—Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan
    Health Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan)

  • Cheng-Ming Hsu

    (Department of Otolaryngology—Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan
    Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan)

  • Ching-Yuan Wu

    (Department of Traditional Chinese Medicine, Chiayi Branch of Chang-Gung Memorial Hospital, Chiayi 613, Taiwan
    School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan)

  • Wei-Tai Shih

    (Department of Traditional Chinese Medicine, Chiayi Branch of Chang-Gung Memorial Hospital, Chiayi 613, Taiwan
    School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan)

  • Ming-Shao Tsai

    (Department of Otolaryngology—Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan
    Health Information and Epidemiology Laboratory, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan
    Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
    Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan)

Abstract

Background: Peritonsillar abscess (PTA) is an infectious emergency in the head and neck, and patients with end-stage renal disease (ESRD) have an immunocompromised status. However, no relevant research has focused on the ESRD–PTA relationship. This study explored PTA in ESRD patients and their prognosis. Methods: We identified 157,026 patients diagnosed as having ESRD over January 1997 to December 2013 from Taiwan’s National Health Insurance Research Database (NHIRD). Each patient with ESRD (hereafter, patients) was matched with one control without chronic kidney disease (CKD; hereafter, controls) by sex, age, urbanization level, and income. Next, PTA incidence until death or the end of 2013 was compared between the two groups, and the relative risk of PTA was analyzed using a multiple logistic regression model. Results: The patients had a significantly higher PTA incidence than did the controls (incidence rate ratio: 2.02, 95% confidence interval [CI]: 1.40–2.91, p < 0.001). The Kaplan–Meier analysis revealed that the patients had a higher cumulative incidence of PTA than did the controls ( p < 0.001). In Cox regression analysis, the patients had nearly twofold higher PTA risk (adjusted hazard ratio [HR]: 1.98, 95% CI: 1.37–2.86, p < 0.001). The between-group differences in the PTA-related hospital stay length (8.1 ± 10.3 days in patients and 5.7 ± 4.6 days in controls, p = 0.09), consequent deep-neck infection complication (4.2% in patients and 6.3% in controls, p = 0.682), and mortality (0.0% in both groups) were nonsignificant. Conclusions: Although ESRD does not predict a poor prognosis of PTA, it is an independent PTA risk factor.

Suggested Citation

  • Geng-He Chang & Ang Lu & Yao-Hsu Yang & Chia-Yen Liu & Pey-Jium Chang & Chuan-Pin Lee & Yao-Te Tsai & Cheng-Ming Hsu & Ching-Yuan Wu & Wei-Tai Shih & Ming-Shao Tsai, 2021. "High Risk of Peritonsillar Abscess in End-Stage Renal Disease Patients: A Nationwide Real-World Cohort Study," IJERPH, MDPI, vol. 18(13), pages 1-10, June.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:13:p:6775-:d:581057
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/13/6775/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/13/6775/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Ming-Shao Tsai & Geng-He Chang & Wei-Ming Chen & Chia-Yen Liu & Meng-Hung Lin & Pey-Jium Chang & Tsung-Yu Huang & Yao-Te Tsai & Ching-Yuan Wu & Cheng-Ming Hsu & Yao-Hsu Yang, 2019. "The Association Between Decompensated Liver Cirrhosis and Deep Neck Infection: Real-World Evidence," IJERPH, MDPI, vol. 16(20), pages 1-11, October.
    2. Chi-Shin Wu & Mei-Shu Lai & Susan Shur-Fen Gau & Sheng-Chang Wang & Hui-Ju Tsai, 2014. "Concordance between Patient Self-Reports and Claims Data on Clinical Diagnoses, Medication Use, and Health System Utilization in Taiwan," PLOS ONE, Public Library of Science, vol. 9(12), pages 1-16, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Meng-Chang Ding & Cheng-Ming Hsu & Stanley Yung-Chuan Liu & Yi-Chan Lee & Yao-Hsu Yang & Chia-Yen Liu & Geng-He Chang & Yao-Te Tsai & Li-Ang Lee & Pei-Rung Yang & Hsueh-Yu Li & Ming-Shao Tsai, 2021. "Deep Neck Infection Risk in Patients with Sleep Apnea: Real-World Evidence," IJERPH, MDPI, vol. 18(6), pages 1-10, March.
    2. Pin-Han Peng & Meng-Yun Tsai & Sheng-Yu Lee & Po-Cheng Liao & Yu-Chiau Shyu & Liang-Jen Wang, 2020. "Attention-Deficit/Hyperactivity Disorder, Its Pharmacotherapy, and Adrenal Gland Dysfunction: A Nationwide Population-Based Study in Taiwan," IJERPH, MDPI, vol. 17(10), pages 1-10, May.
    3. Chien-Hua Chen & Cheng-Li Lin & Chia-Hung Kao, 2020. "The Risk of Venous Thromboembolism in Patients with Gallstones," IJERPH, MDPI, vol. 17(8), pages 1-12, April.
    4. Bharadwaj, Prashant & Pai, Mallesh M. & Suziedelyte, Agne, 2017. "Mental health stigma," Economics Letters, Elsevier, vol. 159(C), pages 57-60.
    5. Meng-Ting Wang & Yun-Han Wang & Hsin-An Chang & Chen-Liang Tsai & Ya-Sung Yang & Chen Wei Lin & Cheng-Chin Kuo & Yu-Juei Hsu, 2017. "Benzodiazepine and Z-drug use and risk of pneumonia in patients with chronic kidney disease: A population-based nested case-control study," PLOS ONE, Public Library of Science, vol. 12(7), pages 1-16, July.
    6. Che-Hsiung Wu & Ya-Wen Yang & Szu-Chun Hung & Ko-Lin Kuo & Kwan-Dun Wu & Vin-Cent Wu & Tsung-Cheng Hsieh & for the National Taiwan University Study Group on Acute Renal Failure (NSARF), 2017. "Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease," PLOS ONE, Public Library of Science, vol. 12(5), pages 1-17, May.
    7. Hilal Al Shamsi & Abdullah Ghthaith Almutairi & Sulaiman Salim Al Mashrafi, 2018. "Implications of Disagreement Between Self-Reporting and Objective Measures: A Scoping Review," Global Journal of Health Science, Canadian Center of Science and Education, vol. 10(6), pages 199-199, June.
    8. Syuan-Yu Hong & Lei Wan & Hui-Ju Lin & Cheng-Li Lin & Chang-Ching Wei, 2020. "Long-Term Ambient Air Pollutant Exposure and Risk of Recurrent Headache in Children: A 12-Year Cohort Study," IJERPH, MDPI, vol. 17(23), pages 1-15, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:13:p:6775-:d:581057. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.