Author
Listed:
- Marianna Mile
(Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
Both authors contributed equally to this manuscript.)
- László Balogh
(Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
Both authors contributed equally to this manuscript.)
- Gábor Papp
(Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary
Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary)
- József Márton Pucsok
(Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary)
- Krisztina Szabó
(Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary)
- Lilla Barna
(Institute of Sport Sciences, University of Debrecen, 4032 Debrecen, Hungary)
- Zoltán Csiki
(Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary)
- István Lekli
(Institute of Healthcare Industry, University of Debrecen, 4032 Debrecen, Hungary
Department of Pharmacology, Faculty of Pharmacy, University of Debrecen, 4032 Debrecen, Hungary)
Abstract
Sarcopenia, defined as loss of muscle mass and strength, develops gradually with aging or after chronic disease. Efforts are ongoing to identify the best interventions that can slow down or stop sarcopenia. Nutrition-based interventions and exercise therapy may be beneficial; however, pharmacotherapy also could play a role. The effect of ACE inhibitors on physical performance is controversial. The present study investigates the impact of functional training on sarcopenia in the presence or absence of ACEi in elderly females. A total of 35 women over 65 years of age were selected for two groups on the basis that they were taking ACEi ( n = 18) or not ( n = 17). All subjects conducted a training program two times a week for 6 months. We examined various factors related to sarcopenia. After completing the short physical performance battery (SPPB) test, we found a significant improvement after 6 months of functional training. SPPB values of the ACEi group were significantly lower at the beginning of the study; however, we observed no difference between the SPPB results of the two groups after the training period. We conducted further studies to measure posture and spine mobility. Our Schober and Cobra test results revealed significantly improved spine mobility (both flexor and extensor) in both groups after 6 months of training. Furthermore, the grip strength of the hands, studied by an electric dynamometer, was significantly improved in both groups at the end of the training period. Our results indicated that functional training may improve body composition and muscle strength in patients diagnosed with sarcopenia. Furthermore, ACEi may be a helpful additional therapy in older adult patients suffering from severe sarcopenia.
Suggested Citation
Marianna Mile & László Balogh & Gábor Papp & József Márton Pucsok & Krisztina Szabó & Lilla Barna & Zoltán Csiki & István Lekli, 2021.
"Effects of Functional Training on Sarcopenia in Elderly Women in the Presence or Absence of ACE Inhibitors,"
IJERPH, MDPI, vol. 18(12), pages 1-11, June.
Handle:
RePEc:gam:jijerp:v:18:y:2021:i:12:p:6594-:d:577843
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