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High Level of Physical Activity Reduces the Risk of Renal Progression in Hypertensive Patients

Author

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  • Po-Ya Chang

    (Department of Leisure Industry and Health Promotion, National Taipei University of Nursing and Health Sciences, Taipei City 11219, Taiwan)

  • Shu-Yu Lyu

    (Department of Leisure Industry and Health Promotion, National Taipei University of Nursing and Health Sciences, Taipei City 11219, Taiwan)

  • Yuh-Feng Lin

    (Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei City 11031, Taiwan)

  • Chun-Ching Huang

    (Department of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei City 11219, Taiwan)

Abstract

Physical activity has long been associated with chronic diseases. However, the association between physical activity and renal progression in hypertensive patients remains unclear. This study investigated the relationship between the level of physical activity and renal function in hypertensive patients. We analyzed 3543 patients with hypertension. Data on patients’ demographic characteristics, comorbidities, physical activity, and lifestyle characteristics were collected via questionnaires. An estimated glomerular filtration rate (eGFR) that was reduced by more than 25% from the baseline eGFR was defined as renal progression. This study divided physical activity into three levels (low, moderate, and high) based on their metabolic equivalent of tasks (METs) levels. The mean age was 63.32 ± 12.29 years. After we adjusted for covariates, renal progression was significantly higher among patients with low levels of physical activity (odds ratio (OR), 1.39; 95% confidence interval (CI), 1.01–1.90)) and moderate levels of physical activity (OR, 1.39; 95% CI, 1.04–1.86) than among patients with high levels of physical activity. We found a significant association between physical activity and renal progression in hypertensive patients, especially in elderly patients and men. Therefore, to reduce the risk of renal progression, we recommend that clinicians should encourage patients to improve their physical activity.

Suggested Citation

  • Po-Ya Chang & Shu-Yu Lyu & Yuh-Feng Lin & Chun-Ching Huang, 2020. "High Level of Physical Activity Reduces the Risk of Renal Progression in Hypertensive Patients," IJERPH, MDPI, vol. 17(5), pages 1-11, March.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:5:p:1669-:d:328283
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    References listed on IDEAS

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    1. Ling-I Chen & Jinn-Yuh Guh & Kwan-Dun Wu & Yung-Ming Chen & Mei-Chuan Kuo & Shang-Jyh Hwang & Tzu-Hui Chen & Hung-Chun Chen, 2014. "Modification of Diet in Renal Disease (MDRD) Study and CKD Epidemiology Collaboration (CKD-EPI) Equations for Taiwanese Adults," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-9, June.
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