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Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study

Author

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  • Mengyun Sui

    (NHC Key Laboratory of Health Technology Assessment, School of Public Health, Fudan University, Dongan Road 130, Shanghai 200032, China)

  • Long Xue

    (NHC Key Laboratory of Health Technology Assessment, School of Public Health, Fudan University, Dongan Road 130, Shanghai 200032, China)

  • Xiaohua Ying

    (NHC Key Laboratory of Health Technology Assessment, School of Public Health, Fudan University, Dongan Road 130, Shanghai 200032, China)

Abstract

The prevalence and mortality rates of diabetes are increasing globally, posing severe challenges to health systems. Acupuncture is used worldwide as a non-drug treatment for diabetes. However, empirical evidence of the effect of combined acupuncture and drug treatments on diabetic-associated mortality is limited. This study aimed to examine this association of acupuncture treatment with mortality of type 2 diabetes based on real-world data. A four-year cohort study was conducted in Shanghai between 2015 and 2018, The database consisted of 37,718 patients (acupuncture group: 6865 type 2 diabetes mellitus (T2DM) patients, non-acupuncture (control) group: 30,853 T2DM patients) in 2016. The objective was to analyze the impact of receiving acupuncture prescriptions for diabetes in 2016 on all-cause mortality in 2018 based on real-world data. An Inverse Probability Weighted Regression Adjustment (IPWRA) and Propensity Score Matching (PSM) were used to minimize the bias due to potential confounding variables to increase the reliability of differences in comparisons between the two groups. Our inverse probability weighted regression results suggest that the coefficient of the key dependent variable of accepted acupuncture in 2016 was negative (coefficient: −0.0002; 95% CI: −0.0024–0.0019, p = 0.857), but it is not statistically significant. In robustness check, PSM with the nearest-neighbor method with replacement at a 1:4 ratio and 1:3 ratio and kernel matching showed that the average treatment effect was negative. Therefore, there was a negative correlation between acupuncture combined with other drugs and the mortality of diabetic patients, but it was not statistically significant.

Suggested Citation

  • Mengyun Sui & Long Xue & Xiaohua Ying, 2020. "Association of Acupuncture Treatment with Mortality of Type 2 Diabetes in China: Evidence of a Real-World Study," IJERPH, MDPI, vol. 17(21), pages 1-10, October.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:21:p:7801-:d:434364
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    References listed on IDEAS

    as
    1. Zhiqun Shu & Ling Wang & Xiaoming Sun, 2019. "An evaluation of the effects of general practitioner–supported patient noncommunicable diseases control model in Shanghai, China," International Journal of Health Planning and Management, Wiley Blackwell, vol. 34(3), pages 947-959, July.
    2. Strumpf, Erin & Ammi, Mehdi & Diop, Mamadou & Fiset-Laniel, Julie & Tousignant, Pierre, 2017. "The impact of team-based primary care on health care services utilization and costs: Quebec’s family medicine groups," Journal of Health Economics, Elsevier, vol. 55(C), pages 76-94.
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