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The Cost-Effectiveness of Hepatitis C Virus Screening Strategies among Recently Arrived Migrants in the Netherlands

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  • Mohamed N.M.T. Al Khayat

    (Department of Health Sciences, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands
    Department of Clinical Pharmacy, Isala Hospital Zwolle, 8025 BT Zwolle, The Netherlands)

  • Job F.H. Eijsink

    (Department of Health Sciences, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands
    Department of Clinical Pharmacy, Isala Hospital Zwolle, 8025 BT Zwolle, The Netherlands
    Department of Economics, Faculty of Economics & Business, University of Groningen, Econometrics & Finance, 9712 CP Groningen, The Netherlands)

  • Maarten J. Postma

    (Department of Health Sciences, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands
    Department of Economics, Faculty of Economics & Business, University of Groningen, Econometrics & Finance, 9712 CP Groningen, The Netherlands
    Unit of Pharmacotherapy, Epidemiology & Economics, Department of Pharmacy, University of Groningen, 9712 CP Groningen, The Netherlands)

  • Jan C. Wilschut

    (Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands)

  • Marinus van Hulst

    (Department of Health Sciences, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands
    Department of Clinical Pharmacy, Martini Hospital Groningen, 9728 NT Groningen, The Netherlands)

Abstract

Objective: We aimed to assess the cost-effectiveness of hepatitis C virus (HCV) screening strategies among recently arrived migrants in the Netherlands. Methods: A Markov model was used to estimate the health effects and costs of HCV screening from the healthcare perspective. A cohort of 50,000 recently arrived migrants was used. In this cohort, three HCV screening strategies were evaluated: (i) no screening, (ii) screening of migrants from HCV-endemic countries and (iii) screening of all migrants. Results: Strategy (ii) screening of migrants from HCV-endemic countries compared to strategy (i) no screening, yielded an incremental cost-effectiveness ratio (ICER) of €971 per quality-adjusted life-years (QALYs) gained. Strategy (iii) screening of all migrants compared with strategy (ii) screening of migrants from HCV-endemic countries yielded an ICER of €1005 per QALY gained. The budget impact of strategy (ii) screening of migrants from HCV-endemic countries and strategy (iii) screening of all migrants was €13,752,039 and €20,786,683, respectively. Conclusion: HCV screening is cost-effective. However, the budget impact may have a strong influence on decision making.

Suggested Citation

  • Mohamed N.M.T. Al Khayat & Job F.H. Eijsink & Maarten J. Postma & Jan C. Wilschut & Marinus van Hulst, 2020. "The Cost-Effectiveness of Hepatitis C Virus Screening Strategies among Recently Arrived Migrants in the Netherlands," IJERPH, MDPI, vol. 17(17), pages 1-13, August.
  • Handle: RePEc:gam:jijerp:v:17:y:2020:i:17:p:6091-:d:402220
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    1. Albert Do & Yash Mittal & AnnMarie Liapakis & Elizabeth Cohen & Hong Chau & Claudia Bertuccio & Dana Sapir & Jessica Wright & Carol Eggers & Kristine Drozd & Maria Ciarleglio & Yanhong Deng & Joseph K, 2015. "Drug Authorization for Sofosbuvir/Ledipasvir (Harvoni) for Chronic HCV Infection in a Real-World Cohort: A New Barrier in the HCV Care Cascade," PLOS ONE, Public Library of Science, vol. 10(8), pages 1-15, August.
    2. David J. McLernon & John Dillon & Peter T. Donnan, 2008. "Systematic Review: Health-State Utilities in Liver Disease: A Systematic Review," Medical Decision Making, , vol. 28(4), pages 582-592, July.
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    Cited by:

    1. David McDaid & A-La Park, 2021. "Modelling the Economic Impact of Reducing Loneliness in Community Dwelling Older People in England," IJERPH, MDPI, vol. 18(4), pages 1-16, February.

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