IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i17p6088-d402168.html
   My bibliography  Save this article

Exposure to ZnO/TiO 2 Nanoparticles Affects Health Outcomes in Cosmetics Salesclerks

Author

Listed:
  • Ching-Chang Lee

    (Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
    Research Center for Environmental Trace Toxic Substances, National Cheng Kung University, Tainan 701, Taiwan)

  • Yi-Hsin Lin

    (Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan)

  • Wen-Che Hou

    (Department of Environmental Engineering, National Cheng Kung University, Tainan 701, Taiwan)

  • Meng-Han Li

    (Department of Environmental Engineering, National Cheng Kung University, Tainan 701, Taiwan)

  • Jung-Wei Chang

    (Institute of Environmental and Occupational Health Sciences, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan)

Abstract

Concerns about the effects of nanoparticles (NPs) on human health are being raised by researchers because the risks of nanocosmetics like sunscreen are unknown. We explored the association between urinary oxidative stress markers and exposure of cosmetics salesclerks to 20 cosmetics that might contain titanium dioxide (TiO 2 )/zinc oxide (ZnO) NPs. We then recruited 40 cosmetics salesclerks and 24 clothing salesclerks and categorized them based on their exposure to ZnO and TiO 2 NPs. Nineteen and 15 samples met the EU definition for TiO 2 and ZnO nanomaterials, respectively. Participants with a higher co-exposure index of ZnO and TiO 2 NPs had a significantly higher base level of urinary 8-hydroxy-2′-deoxyguanosin (8-OHdG) concentrations than the lower co-exposure group (5.82 vs. 2.85 ng/mL, p < 0.001). After potential confounding factors had been adjusted for, the TiO 2 and ZnO NP co-exposure index was significantly positively associated with the urinary 8-OHdG base concentration (β = 0.308, 95% CI = 0.106 to 0.510) and the creatinine-adjusted concentration (β = 0.486, 95% CI = 0.017 to 0.954). Current evidence suggests that the likelihood of harm from using sunscreens containing nanoparticles might result in higher urinary 8-OHdG. However, our limited number and types of sample cosmetics might underestimate the risk.

Suggested Citation

  • Ching-Chang Lee & Yi-Hsin Lin & Wen-Che Hou & Meng-Han Li & Jung-Wei Chang, 2020. "Exposure to ZnO/TiO 2 Nanoparticles Affects Health Outcomes in Cosmetics Salesclerks," IJERPH, MDPI, vol. 17(17), pages 1-12, August.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:17:p:6088-:d:402168
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/17/6088/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/17/6088/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Matteo Crosera & Andrea Prodi & Marcella Mauro & Marco Pelin & Chiara Florio & Francesca Bellomo & Gianpiero Adami & Pietro Apostoli & Giuseppe De Palma & Massimo Bovenzi & Marco Campanini & Francesca, 2015. "Titanium Dioxide Nanoparticle Penetration into the Skin and Effects on HaCaT Cells," IJERPH, MDPI, vol. 12(8), pages 1-16, August.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. S. A. Basir & N. A. Hasmin & M. R. Othman & A. B. Munir, 2024. "Nanocosmetics Labelling Framework for Malaysia with Reference to the EU," Journal of Consumer Policy, Springer, vol. 47(1), pages 165-195, March.
    2. Xishan Li & Chengyan Wang & Nan Li & Yali Gao & Zhonglei Ju & Guoxiang Liao & Deqi Xiong, 2021. "Combined Effects of Elevated Temperature and Crude Oil Pollution on Oxidative Stress and Apoptosis in Sea Cucumber ( Apostichopus japonicus , Selenka)," IJERPH, MDPI, vol. 18(2), pages 1-16, January.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:17:p:6088-:d:402168. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.