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Dispensing Practices of Fixed Dose Combination Controller Therapy for Asthma in Australian Children and Adolescents

Author

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  • Nusrat Homaira

    (Discipline of Paediatrics, School of Women’s and Children’s Health, Faculty of Medicine, The University of New South Wales, Sydney 2052, Australia
    Respiratory Department, Sydney Children’s Hospital, Sydney 2031, Australia)

  • Benjamin Daniels

    (Medicines Policy Research Unit, Centre for Big Data Research in Health, Sydney 2052, Australia)

  • Sallie Pearson

    (Medicines Policy Research Unit, Centre for Big Data Research in Health, Sydney 2052, Australia)

  • Adam Jaffe

    (Discipline of Paediatrics, School of Women’s and Children’s Health, Faculty of Medicine, The University of New South Wales, Sydney 2052, Australia
    Respiratory Department, Sydney Children’s Hospital, Sydney 2031, Australia)

Abstract

The Australian Asthma Handbook does not recommend use of fixed dose combination (FDC) controller medicines for asthma in children aged ≤5 years. FDCs are only recommended in children and adolescents (aged 6–18 years) not responding to initial inhaled corticosteroid (ICS) therapy. Using Pharmaceutical Benefits Scheme dispensing claims from 2013–2018, we examined the annual incident FDC dispensing and the incident FDC dispensing without prior ICS up to 365 days. We also determined cost of FDCs to government and patients. During 2013–2018, there were 35,635 FDC initiations and 31,368 (88%) did not have a preceding ICS dispensing. The annual incidence of FDC dispensing declined from 14.7 to 7.2/1000 children. Incidence of FDC dispensing/1000 children without a preceding ICS declined from 2.1 to 0.5 in children aged 1–2 years, 7.2 to 1.7 in 3–5 years, 14.8 to 5.1 in 6–11 years, and 18.6 to 11.9 in ≥12years. The cost of FDCs was 7.8 million Australian dollars (AUD); of which 4.4 million AUD was to government and 3.3 million AUD was to patient. Despite inappropriate dispensing of FDCs in children aged ≤5 years, incidence of FDC dispensing and more importantly incidence without a preceding ICS is declining in Australia.

Suggested Citation

  • Nusrat Homaira & Benjamin Daniels & Sallie Pearson & Adam Jaffe, 2020. "Dispensing Practices of Fixed Dose Combination Controller Therapy for Asthma in Australian Children and Adolescents," IJERPH, MDPI, vol. 17(16), pages 1-7, August.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:16:p:5645-:d:394879
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