IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i12p4219-d370945.html
   My bibliography  Save this article

A Serosurvey Identifying Vulnerability to Measles in Health Care Workers. A Hospital-Based Prospective Seroprevalence Study

Author

Listed:
  • Jana Malinová

    (Third Faculty of Medicine, Charles University in Prague, 10000 Prague, Czech Republic
    Faculty Hospital Kralovské Vinohrady, 10000 Prague, Czech Republic)

  • Marek Petráš

    (Third Faculty of Medicine, Charles University in Prague, 10000 Prague, Czech Republic)

  • Alexander M. Čelko

    (Third Faculty of Medicine, Charles University in Prague, 10000 Prague, Czech Republic)

Abstract

The aim of this serological survey was to assess the persistence of measles antibodies among health care workers (HCWs) at risk of incidental measles. A prospective study of measles-specific antibodies in serum samples obtained from a total of 2782 participants aged 19–89 years was conducted between May 2018 and December 2019. The seropositivity rate of 93.7% (95% CI: 92.4–94.9%) in fully vaccinated participants aged 19–48 years was significantly lower than that of 98.0% (95% CI: 96.5–99.0%) in participants naturally immunised before 54 years. A cohort of those born in 1971–1975, vaccinated predominantly with one dose, showed lower seropositivity persistence (86.6%) than those fully vaccinated with two doses or naturally immunised. Otherwise, seropositivity was not markedly influenced by sex, age, smoking status, overweight, obesity or concomitant disease. The presence of sufficient antibody levels in a high proportion of HCWs irrespective of the way they acquired immunity is a favourable finding for managing incidental measles; hence, in the presence of a risk of a measles outbreak, it would be possible to perform targeted vaccination of only at-risk HCWs with a history of incomplete vaccination or missing information about the way in which immunity is acquired.

Suggested Citation

  • Jana Malinová & Marek Petráš & Alexander M. Čelko, 2020. "A Serosurvey Identifying Vulnerability to Measles in Health Care Workers. A Hospital-Based Prospective Seroprevalence Study," IJERPH, MDPI, vol. 17(12), pages 1-10, June.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:12:p:4219-:d:370945
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/12/4219/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/12/4219/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ines Drenjančević & Senka Samardžić & Ana Stupin & Katalin Borocz & Peter Nemeth & Timea Berki, 2022. "Measles Vaccination and Outbreaks in Croatia from 2001 to 2019; A Comparative Study to Other European Countries," IJERPH, MDPI, vol. 19(7), pages 1-12, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:12:p:4219-:d:370945. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.