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Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery

Author

Listed:
  • Luigi Laino

    (Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania “Luigi Vanvitelli”, 80100 Napoli, Italy)

  • Marco Cicciù

    (Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina (ME), Italy)

  • Luca Fiorillo

    (Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania “Luigi Vanvitelli”, 80100 Napoli, Italy
    Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina (ME), Italy)

  • Salvatore Crimi

    (Department of Biomedical and Surgical and Biomedical Sciences Catania University, 95125 Catania (CT), Italy)

  • Alberto Bianchi

    (Department of Biomedical and Surgical and Biomedical Sciences Catania University, 95125 Catania (CT), Italy)

  • Giulia Amoroso

    (Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina (ME), Italy)

  • Ines Paola Monte

    (Department of General Surgery and Medical-Surgery Specialties, University of Catania, 95125 Catania (CT), Italy
    Department of Cardio-Thorax-Vascular and Transplant, A.O.U. Policlinico Catania, 95125 Catania (CT), Italy)

  • Alan Scott Herford

    (Department of Maxillofacial Surgery, Loma Linda University, Loma Linda, CA 92350, USA)

  • Gabriele Cervino

    (Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina (ME), Italy)

Abstract

Background: Haemophilia is a disease of genetic origin, which causes a defect in blood coagulation. Under normal conditions, in the case of leakage from the blood vessels, the blood forms a clot that reduces or blocks the bleeding. This process involves the activation of several plasma proteins in a cascade-like species. Two of these proteins, produced in the liver, factor VIII and factor IX, are deficient or present a functional defect in people with haemophilia. Because of this deficit, the haemophiliacs easily suffer external and internal bleeding. Surgical treatment of these patients is to be observed, and often their treatment is delayed due to unclear guidelines and risks in treating these patients. The aim is to provide clear guidelines in the case of surgical treatment of these patients. Methods: In this study, we have considered all the guidelines that refer to the gold-maxillofacial surgery, focusing on the literature of the last 10 years. Results: Surely, this collection of guidelines will favor the choice of the clinician towards safer and predictable protocols. This study does not want to create a guideline but evaluates the literature of the last 10 years, and highlights the latest for the treatment of these patients., with the aim of informing the pathology and at the same time making the surgical maneuvers safer. Conclusions: Despite the research of literature has produced few results, it was nevertheless possible to draw up a guideline thanks to additional information extrapolated from textbooks and other scientific articles. According to the guidelines, it is possible to proceed to the treatment of these patients, if with appropriate therapy in a safe and risk-free manner.

Suggested Citation

  • Luigi Laino & Marco Cicciù & Luca Fiorillo & Salvatore Crimi & Alberto Bianchi & Giulia Amoroso & Ines Paola Monte & Alan Scott Herford & Gabriele Cervino, 2019. "Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery," IJERPH, MDPI, vol. 16(8), pages 1-12, April.
    • Handle: RePEc:gam:jijerp:v:16:y:2019:i:8:p:1386-:d:223707
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    References listed on IDEAS

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    1. Neil Savage, 2014. "Born in the blood," Nature, Nature, vol. 515(7528), pages 158-159, November.
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    1. Damien Offner & Gabriel Fernandez De Grado & Marion Strub & Laure Belotti & Stéphanie Deboscker & Anne-Marie Musset, 2020. "Mobile Dental Delivery System: An Effective Protocol for Hygiene and Disinfection," IJERPH, MDPI, vol. 17(5), pages 1-11, March.
    2. Khrystyna Zhurakivska & Giuseppe Troiano & Marco Montella & Lorenzo Lo Muzio & Luca Fiorillo & Gabriele Cervino & Marco Cicciù & Cesare D’Amico & Rosario Rullo & Gregorio Laino & Dario Di Stasio & Lui, 2020. "Oral Health and Molecular Aspects of Malignant Fibrous Histiocytoma Patients: A Systematic Review of the Literature," IJERPH, MDPI, vol. 17(4), pages 1-11, February.
    3. Lior Levy & Abbas Smiley & Rifat Latifi, 2022. "Adult and Elderly Risk Factors of Mortality in 23,614 Emergently Admitted Patients with Rectal or Rectosigmoid Junction Malignancy," IJERPH, MDPI, vol. 19(15), pages 1-18, July.
    4. Maria Antoniadou & Anestis Intzes & Christos Kladouchas & Iliana Christou & Stavroula Chatzigeorgiou & Martha Plexida & Valantis Stefanidakis & Ioannis Tzoutzas, 2023. "Factors Affecting Water Quality and Sustainability in Dental Practices in Greece," Sustainability, MDPI, vol. 15(11), pages 1-23, June.

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