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Modification of the Association between Visual Impairment and Mortality by Physical Activity: A Cohort Study among the Korean National Health Examinees

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  • Kyoung-Nam Kim

    (Division of Public Health and Preventive Medicine, Seoul National University Hospital, Seoul 03080, Korea
    Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Korea)

  • Sang Jun Park

    (Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Korea
    Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam 13620, Korea)

  • Woosung Kim

    (Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Korea)

  • Jungmin Joo

    (Division of Public Health and Preventive Medicine, Seoul National University Hospital, Seoul 03080, Korea)

  • Haebin Kim

    (Department of Psychiatry, Kyung Hee University Hospital, Seoul 02447, Korea)

  • Kyae Hyung Kim

    (Division of Public Health and Preventive Medicine, Seoul National University Hospital, Seoul 03080, Korea
    Department of Family Medicine, Seoul National University College of Medicine, Seoul 03080, Korea)

  • Ji Hoon Sohn

    (Division of Public Health and Preventive Medicine, Seoul National University Hospital, Seoul 03080, Korea
    Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul 03080, Korea)

  • Yong Jin Kwon

    (Division of Public Health and Preventive Medicine, Seoul National University Hospital, Seoul 03080, Korea
    Department of Forensic Medicine, Seoul National University College of Medicine, Seoul 03080, Korea)

Abstract

The association between visual impairment and higher mortality remains unclear. In addition, evidence is lacking on the interaction between visual function and physical activity on mortality. We used data of individuals with no disability or with visual impairment among those who participated in the National Health Screening Program in Korea in 2009 or 2010. We constructed Cox proportional hazard models adjusted for potential confounders to evaluate the independent association between visual impairment and mortality. More severe visual impairment was associated with higher all-cause mortality ( p -value for trend = 0.03) and mortality due to cardiovascular diseases ( p -value for trend = 0.02) and that due to other diseases ( p -value for trend = 0.01). We found an interaction on an additive scale between visual impairment and no physical activity on all-cause mortality (relative excess risk due to interaction = 1.34, 95% confidence interval: 0.37, 2.30, p -value = 0.01). When we stratified the study population by physical activity, the association between visual impairment and mortality was only found among individuals who did not engage in regular physical activity ( p -value for trend = 0.01). We found an independent association between visual impairment and mortality and modification of this association by physical activity.

Suggested Citation

  • Kyoung-Nam Kim & Sang Jun Park & Woosung Kim & Jungmin Joo & Haebin Kim & Kyae Hyung Kim & Ji Hoon Sohn & Yong Jin Kwon, 2019. "Modification of the Association between Visual Impairment and Mortality by Physical Activity: A Cohort Study among the Korean National Health Examinees," IJERPH, MDPI, vol. 16(22), pages 1-12, November.
  • Handle: RePEc:gam:jijerp:v:16:y:2019:i:22:p:4386-:d:285462
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    Citations

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    Cited by:

    1. Rosie K. Lindsay & Francesco Di Gennaro & Peter M. Allen & Mark A. Tully & Claudia Marotta & Damiano Pizzol & Trish Gorely & Yvonne Barnett & Lee Smith, 2021. "Correlates of Physical Activity among Adults with Sight Loss in High-Income-Countries: A Systematic Review," IJERPH, MDPI, vol. 18(22), pages 1-24, November.

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