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Remission of Type 2 Diabetes Mellitus after Bariatric Surgery: Fact or Fiction?

Author

Listed:
  • Dimitrios Tsilingiris

    (First Department of Propaedeutic Internal Medicine and Diabetes Center, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens 11527, Greece)

  • Chrysi Koliaki

    (First Department of Propaedeutic Internal Medicine and Diabetes Center, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens 11527, Greece)

  • Alexander Kokkinos

    (First Department of Propaedeutic Internal Medicine and Diabetes Center, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens 11527, Greece)

Abstract

Although type 2 diabetes mellitus (T2DM) has been traditionally viewed as an intractable chronic medical condition, accumulating evidence points towards the notion that a complete remission of T2DM is feasible following a choice of medical and/or surgical interventions. This has been paralleled by increasing interest in the establishment of a universal definition for T2DM remission which, under given circumstances, could be considered equivalent to a “cure”. The efficacy of bariatric surgery in particular for achieving glycemic control has highlighted surgery as a candidate curative intervention for T2DM. Herein, available evidence regarding available surgical modalities and the mechanisms that drive metabolic amelioration after bariatric surgery are reviewed. Furthermore, reports from observational and randomized studies with regard to T2DM remission are reviewed, along with concepts relevant to the variety of definitions used for T2DM remission and other potential sources of discrepancy in success rates among different studies.

Suggested Citation

  • Dimitrios Tsilingiris & Chrysi Koliaki & Alexander Kokkinos, 2019. "Remission of Type 2 Diabetes Mellitus after Bariatric Surgery: Fact or Fiction?," IJERPH, MDPI, vol. 16(17), pages 1-22, August.
    • Handle: RePEc:gam:jijerp:v:16:y:2019:i:17:p:3171-:d:262483
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    Cited by:

    1. Cláudia Santos & Manuel Carvalho & Leandro Oliveira & António Palmeira & Luís Monteiro Rodrigues & João Gregório, 2022. "The Long-Term Association between Physical Activity and Weight Regain, Metabolic Risk Factors, Quality of Life and Sleep after Bariatric Surgery," IJERPH, MDPI, vol. 19(14), pages 1-11, July.

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