IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v16y2019i15p2744-d253609.html
   My bibliography  Save this article

Effects of Maternal Prenatal Multi-Micronutrient Supplementation on Growth and Development until 3 Years of Age

Author

Listed:
  • Gang Cheng

    (Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Kaifu District, Changsha 410078, Hunan, China)

  • Tingting Sha

    (Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Kaifu District, Changsha 410078, Hunan, China)

  • Xiao Gao

    (Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Kaifu District, Changsha 410078, Hunan, China)

  • Xialing Wu

    (Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Kaifu District, Changsha 410078, Hunan, China)

  • Qianling Tian

    (Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Kaifu District, Changsha 410078, Hunan, China)

  • Fan Yang

    (Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Kaifu District, Changsha 410078, Hunan, China)

  • Yan Yan

    (Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Kaifu District, Changsha 410078, Hunan, China)

Abstract

At present, there is insufficient evidence on whether prenatal multi-micronutrient (MM) supplementation can be an antenatal nutritional intervention or not. This study aimed to explore the sustained effect of prenatal MM supplementation on early childhood health. A total of 939 mother–offspring pairs were followed up in the study between 2015 to 2018 in Changsha, China. Information was mainly collected through household surveys at the ages of 1, 3, 6, 8, 12, 18, 24, and 36 months. General linear models and generalized estimating equation models were used to estimate the effects of maternal prenatal MM compared with IFA supplementation on infant growth and development. Offspring of women who used prenatal MM compared with IFA supplements had lower weight-for-age z score (WAZ) (adjusted β: −0.23, 95% CI: (−0.40, −0.06)) and weight-for-length z score (WLZ) (adjusted β: −0.20, 95% CI: (−0.37, −0.02)) at 3 months old, but a reduced risk of obesity at birth (aRR: 0.30, 95% CI: 0.11–0.78) and being overweight at 3 months old (aRR: 0.52, 95% CI: 0.32–0.84). Moreover, offspring of women who used prenatal MM compared with IFA supplements had significantly higher scores for communication (adjusted β: 0.41, 95% CI: 0.61–0.21), gross motor (adjusted β: 0.68, 95% CI: 0.49–0.88), fine motor (adjusted β: 1.64, 95% CI: 1.45–1.84), problem solving (adjusted β: 0.29, 95% CI: 0.10–0.49), and personal–social (adjusted β: 0.90, 95% CI: 0.70–1.10) skills at 36 months old. Prenatal MM supplementation could result in better infant growth in the first few months of life and improve development scores at the age of 3 years compared with IFA supplementation.

Suggested Citation

  • Gang Cheng & Tingting Sha & Xiao Gao & Xialing Wu & Qianling Tian & Fan Yang & Yan Yan, 2019. "Effects of Maternal Prenatal Multi-Micronutrient Supplementation on Growth and Development until 3 Years of Age," IJERPH, MDPI, vol. 16(15), pages 1-16, August.
    • Handle: RePEc:gam:jijerp:v:16:y:2019:i:15:p:2744-:d:253609
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/16/15/2744/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/16/15/2744/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Tingting Sha & Xiao Gao & Cheng Chen & Ling Li & Qiong He & Xialing Wu & Gang Cheng & Qianling Tian & Fan Yang & Yan Yan, 2019. "Associations of Pre-Pregnancy BMI, Gestational Weight Gain and Maternal Parity with the Trajectory of Weight in Early Childhood: A Prospective Cohort Study," IJERPH, MDPI, vol. 16(7), pages 1-13, March.
    2. Xialing Wu & Xiao Gao & Tingting Sha & Guangyu Zeng & Shiping Liu & Ling Li & Cheng Chen & Yan Yan, 2019. "Modifiable Individual Factors Associated with Breastfeeding: A Cohort Study in China," IJERPH, MDPI, vol. 16(5), pages 1-11, March.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Gang Cheng & Tingting Sha & Xiao Gao & Qiong He & Xialing Wu & Qianling Tian & Fan Yang & Cai Tang & Xihong Wu & Qunhui Xie & Yan Yan, 2019. "The Associations between the Duration of Folic Acid Supplementation, Gestational Diabetes Mellitus, and Adverse Birth Outcomes based on a Birth Cohort," IJERPH, MDPI, vol. 16(22), pages 1-15, November.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Carolina Lechosa Muñiz & María Paz-Zulueta & Elsa Cornejo del Río & Sonia Mateo Sota & María Sáez de Adana & María Madrazo Pérez & María Jesús Cabero Pérez, 2019. "Impact of Maternal Smoking on the Onset of Breastfeeding versus Formula Feeding: A Cross-Sectional Study," IJERPH, MDPI, vol. 16(24), pages 1-11, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:16:y:2019:i:15:p:2744-:d:253609. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.