Author
Listed:
- Shandir Ramlagan
(HIV/Aids, STI and TB Unit, Human Sciences Research Council, Private Bag X41, Pretoria 0001, South Africa
Department of Work & Social Psychology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands)
- Karl Peltzer
(HIV/Aids, STI and TB Unit, Human Sciences Research Council, Private Bag X41, Pretoria 0001, South Africa
Department of Research and Innovation, University of Limpopo, Sovenga 0727, South Africa)
- Robert A. C. Ruiter
(Department of Work & Social Psychology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands)
- Nicole A. Barylski
(Miller School of Medicine, University of Miami, 1400 NW 10th Ave, Miami, FL 33136, USA)
- Stephen M. Weiss
(Miller School of Medicine, University of Miami, 1400 NW 10th Ave, Miami, FL 33136, USA)
- Sibusiso Sifunda
(HIV/Aids, STI and TB Unit, Human Sciences Research Council, Private Bag X41, Pretoria 0001, South Africa
Department of Work & Social Psychology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands)
Abstract
The possibility for all babies to be born and remain HIV-negative for the first year of life is achievable in South Africa. HIV-positive mothers’ adherence to their antiretroviral medication is one of the crucial factors to achieve this target. Cross-sectional data were collected at 12 community health centres, over 12 months (2014–2015), from 673 HIV-positive women, less than 6 months pregnant, attending antenatal care, and on Option B treatment. Adherence measures included the Adults AIDS Clinical Trials Group (AACTG) four-day measure, as well as the Visual Analog Scale (VAS) seven-day measure. Bivariate analyses and multivariate logistic regressions are presented. 78.8% of respondents were adherent on AACTG, while 68.8% reported VAS adherence. Bivariate analyses for increased adherence show significant associations with older age, less/no alcohol usage, disclosure of HIV status, higher HIV knowledge, no desire to avoid ARV side effects, low stigma, and low depression. AACTG showed a negative association with intimate partner violence. Multivariable logistic regression on AACTG and VAS adherence rates resulted in unique contributions to increased adherence of older age, less/no alcohol usage, higher HIV knowledge, lack of depression, and non-disclosure. Programs targeting closer side effect monitoring, HIV disclosure, pre-natal depression, alcohol intake, and HIV knowledge need consideration.
Suggested Citation
Shandir Ramlagan & Karl Peltzer & Robert A. C. Ruiter & Nicole A. Barylski & Stephen M. Weiss & Sibusiso Sifunda, 2018.
"Prevalence and Factors Associated with Fixed-Dose Combination Antiretroviral Drugs Adherence among HIV-Positive Pregnant Women on Option B Treatment in Mpumalanga Province, South Africa,"
IJERPH, MDPI, vol. 15(1), pages 1-12, January.
Handle:
RePEc:gam:jijerp:v:15:y:2018:i:1:p:161-:d:127871
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