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Wound Healing Properties of Selected Natural Products

Author

Listed:
  • Nurul ‘Izzah Ibrahim

    (Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia)

  • Sok Kuan Wong

    (Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia)

  • Isa Naina Mohamed

    (Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia)

  • Norazlina Mohamed

    (Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia)

  • Kok-Yong Chin

    (Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia)

  • Soelaiman Ima-Nirwana

    (Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia)

  • Ahmad Nazrun Shuid

    (Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia)

Abstract

Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.

Suggested Citation

  • Nurul ‘Izzah Ibrahim & Sok Kuan Wong & Isa Naina Mohamed & Norazlina Mohamed & Kok-Yong Chin & Soelaiman Ima-Nirwana & Ahmad Nazrun Shuid, 2018. "Wound Healing Properties of Selected Natural Products," IJERPH, MDPI, vol. 15(11), pages 1-23, October.
    • Handle: RePEc:gam:jijerp:v:15:y:2018:i:11:p:2360-:d:178248
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    Cited by:

    1. Renjun Mao & Zhenqing Bai & Jiawen Wu & Ruilian Han & Xuemin Zhang & Weiguo Chai & Zongsuo Liang, 2022. "Transcriptome and HPLC Analysis Reveal the Regulatory Mechanisms of Aurantio-Obtusin in Space Environment-Induced Senna obtusifolia Lines," IJERPH, MDPI, vol. 19(2), pages 1-17, January.

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