IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v15y2018i10p2082-d171423.html
   My bibliography  Save this article

Syncope and Collapse Are Associated with an Increased Risk of Cardiovascular Disease and Mortality in Patients Undergoing Dialysis

Author

Listed:
  • Shih-Ting Huang

    (Division of Nephrology, Taichung Veterans General Hospital, Taichung 407, Taiwan
    Graduate Institute of Public Health, China Medical University, Taichung 404, Taiwan)

  • Tung-Min Yu

    (Division of Nephrology, Taichung Veterans General Hospital, Taichung 407, Taiwan
    Graduate Institute of Biomedical Sciences and School of Medicine, College of Medicine, China Medical University, Taichung 404, Taiwan)

  • Tai-Yuan Ke

    (Division of Nephrology, Ministry of Health and Welfare Chiayi Hospital, Chiayi 600, Taiwan)

  • Ming-Ju Wu

    (Division of Nephrology, Taichung Veterans General Hospital, Taichung 407, Taiwan)

  • Ya-Wen Chuang

    (Division of Nephrology, Taichung Veterans General Hospital, Taichung 407, Taiwan
    Graduate Institute of Public Health, China Medical University, Taichung 404, Taiwan)

  • Chi-Yuan Li

    (Graduate Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan
    Department of Anesthesiology, China Medical University Hospital, Taichung 404, Taiwan)

  • Chih-Wei Chiu

    (Graduate Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan)

  • Cheng-Li Lin

    (Management Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan
    College of Medicine, China Medical University, Taichung 404, Taiwan)

  • Wen-Miin Liang

    (Graduate Institute of Biostatistics, China Medical University, Taichung 404, Taiwan)

  • Tzu-Chieh Chou

    (Department of Public Health, China Medical University, Taichung 404, Taiwan
    Department of Health Risk Management, College of Public Health, China Medical University, Taichung 404, Taiwan)

  • Chia-Hung Kao

    (Graduate Institute of Biomedical Sciences and School of Medicine, College of Medicine, China Medical University, Taichung 404, Taiwan
    Department of Nuclear Medicine and PET Center, China Medical University, Taichung 404, Taiwan
    Department of Bioinformatics and Medical Engineering, Asia University, Taichung 404, Taiwan)

Abstract

Objective : This study explored the impact of syncope and collapse (SC) on cardiovascular events and mortality in patients undergoing dialysis. Methods : Patients undergoing dialysis with SC ( n = 3876) were selected as the study cohort and those without SC who were propensity score-matched at a 1:1 ratio were included as controls. Major adverse cardiovascular events (MACEs), including acute coronary syndrome (ACS), arrhythmia or cardiac arrest, stroke, and overall mortality, were evaluated and compared in both cohorts. Results : The mean follow-up periods until the occurrence of ACS, arrhythmia or cardiac arrest, stroke, and overall mortality in the SC cohort were 3.51 ± 2.90, 3.43 ± 2.93, 3.74 ± 2.97, and 3.76 ± 2.98 years, respectively. Compared with the patients without SC, those with SC had higher incidence rates of ACS (30.1 vs. 24.7 events/1000 people/year), arrhythmia or cardiac arrest (6.75 vs. 3.51 events/1000 people/year), and stroke (51.6 vs. 35.7 events/1000 people/year), with higher overall mortality (127.7 vs. 77.9 deaths/1000 people/year). The SC cohort also had higher risks for ACS, arrhythmia or cardiac arrest, stroke, and overall mortality (adjusted hazard ratios: 1.28 (95% confidence interval (CI) = 1.11–1.46), 2.05 (95% CI = 1.50–2.82), 1.48 (95% CI = 1.33–1.66), and 1.79 (95% CI = 1.67–1.92), respectively) than did the non-SC cohort. Conclusion : SC was significantly associated with cardiovascular events and overall mortality in the patients on dialysis. SC may serve as a prodrome for cardiovascular comorbidities, thereby assisting clinicians in identifying high-risk patients.

Suggested Citation

  • Shih-Ting Huang & Tung-Min Yu & Tai-Yuan Ke & Ming-Ju Wu & Ya-Wen Chuang & Chi-Yuan Li & Chih-Wei Chiu & Cheng-Li Lin & Wen-Miin Liang & Tzu-Chieh Chou & Chia-Hung Kao, 2018. "Syncope and Collapse Are Associated with an Increased Risk of Cardiovascular Disease and Mortality in Patients Undergoing Dialysis," IJERPH, MDPI, vol. 15(10), pages 1-13, September.
    • Handle: RePEc:gam:jijerp:v:15:y:2018:i:10:p:2082-:d:171423
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/15/10/2082/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/15/10/2082/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:15:y:2018:i:10:p:2082-:d:171423. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.