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Visualizing the Heterogeneity of Effects in the Analysis of Associations of Multiple Myeloma with Glyphosate Use. Comments on Sorahan, T. Multiple Myeloma and Glyphosate Use: A Re-Analysis of US Agricultural Health Study (AHS) Data. Int. J. Environ. Res. Public Health 2015, 12 , 1548–1559

Author

Listed:
  • Igor Burstyn

    (Department of Environmental and Occupational Health, Dornsife School of Public Health, Drexel University, Philadelphia, PA 19104, USA)

  • Anneclaire J. De Roos

    (Department of Environmental and Occupational Health, Dornsife School of Public Health, Drexel University, Philadelphia, PA 19104, USA)

Abstract

We address a methodological issue of the evaluation of the difference in effects in epidemiological studies that may arise, for example, from stratum-specific analyses or differences in analytical decisions during data analysis. We propose a new simulation-based method to quantify the plausible extent of such heterogeneity, rather than testing a hypothesis about its existence. We examine the contribution of the method to the debate surrounding risk of multiple myeloma and glyphosate use and propose that its application contributes to a more balanced weighting of evidence.

Suggested Citation

  • Igor Burstyn & Anneclaire J. De Roos, 2016. "Visualizing the Heterogeneity of Effects in the Analysis of Associations of Multiple Myeloma with Glyphosate Use. Comments on Sorahan, T. Multiple Myeloma and Glyphosate Use: A Re-Analysis of US Agric," IJERPH, MDPI, vol. 14(1), pages 1-5, December.
    • Handle: RePEc:gam:jijerp:v:14:y:2016:i:1:p:5-:d:85933
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    References listed on IDEAS

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    1. Tom Sorahan, 2015. "Multiple Myeloma and Glyphosate Use: A Re-Analysis of US Agricultural Health Study (AHS) Data," IJERPH, MDPI, vol. 12(2), pages 1-12, January.
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