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Comments on Scheffler et al . Cytotoxic Evaluation of E-Liquid Aerosol using Different Lung Derived Cell Models. Int. J. Environ. Res. Public Health , 2015, 12 , 12466-12474

Author

Listed:
  • Riccardo Polosa

    (Dipartimento di Medicina Clinica e Sperimentale, Università di Catania, Via Palermo 636, 95121 Catania, Italy)

  • Massimo Caruso

    (Dipartimento di Medicina Clinica e Sperimentale, Università di Catania, Via Palermo 636, 95121 Catania, Italy)

  • Francesca Guarino

    (Dipartimento di Scienze Biomediche e Biotecnologiche, V.le A. Doria 6, 95125 Catania, Italy)

Abstract

There is merit in considering a simple toxicological screening method that evaluates the total cytotoxic potential of e-liquids or electronic cigarettes (ECs) aerosol emissions in one single testing. However, there is growing confusion, with several researchers endorsing their personal solution to the problem. Here, we discuss as an example the recent paper by Scheffler and colleagues, in which the authors suggest that more relevant and well differentiated cell lines from human airways could be the most suitable candidates for toxicological evaluation of ECs aerosol emissions. We advance recommendations for validated protocols and advocate for an international coordinated effort aimed at establishing consensus on methodology.

Suggested Citation

  • Riccardo Polosa & Massimo Caruso & Francesca Guarino, 2016. "Comments on Scheffler et al . Cytotoxic Evaluation of E-Liquid Aerosol using Different Lung Derived Cell Models. Int. J. Environ. Res. Public Health , 2015, 12 , 12466-12474," IJERPH, MDPI, vol. 13(1), pages 1-3, January.
    • Handle: RePEc:gam:jijerp:v:13:y:2016:i:1:p:108-:d:61797
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    References listed on IDEAS

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    1. Stefanie Scheffler & Hauke Dieken & Olaf Krischenowski & Michaela Aufderheide, 2015. "Cytotoxic Evaluation of e-Liquid Aerosol using Different Lung-Derived Cell Models," IJERPH, MDPI, vol. 12(10), pages 1-9, October.
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