IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v12y2015i12p14964-15117d59602.html
   My bibliography  Save this article

Occurrence and Profiles of the Artificial Endocrine Disruptor Bisphenol A and Natural Endocrine Disruptor Phytoestrogens in Urine from Children in China

Author

Listed:
  • Mingyue Zhang

    (Tianjin Centers for Disease Control and Prevention, Tianjin 300171, China
    These authors contributed equally to this work.)

  • Zhenghua Duan

    (Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria/Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Nankai University, Tianjin 300071, China
    School of Environmental Science and Safety Engineering, Tianjin University of Technology, Tianjin 300384, China
    These authors contributed equally to this work.)

  • Yinghong Wu

    (Tianjin Centers for Disease Control and Prevention, Tianjin 300171, China)

  • Zhen Liu

    (Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria/Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Nankai University, Tianjin 300071, China)

  • Ke Li

    (Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria/Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Nankai University, Tianjin 300071, China)

  • Lei Wang

    (Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria/Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Nankai University, Tianjin 300071, China)

Abstract

Background : Exposure to artificial or natural endocrine disruptors, such as bisphenol A (BPA) and phytoestrogens has been demonstrated to have health effects, especially in children. Biomonitoring of BPA and phytoestrogens in human urine can be used to assess the intake levels of these compounds. Methods : In this study, BPA and phytoestrogens in urine specimens ( n = 256) collected from children in China were measured by liquid chromatography (LC)-tandem mass spectrometry (MS/MS). Results : BPA was detected in most specimens, with a geometric mean concentration of 1.58 ng/mL. For the first time, levels of urinary phytoestrogens in Chinese children were reported. Daidzein and enterolactone are the typical isoflavones and lignans compounds in urine, respectively. Conclusions : Relatively high levels of urinary BPA indicate an increasing risk of BPA exposure to Chinese children. Urinary concentrations of daidzein in Chinese children are higher when compared with those reported in the U.S. children, while concentrations of urinary enterolactone and enterodiols are significantly lower. This suggests a significant difference in phytoestrogen intake between the children from China and from the U.S.

Suggested Citation

  • Mingyue Zhang & Zhenghua Duan & Yinghong Wu & Zhen Liu & Ke Li & Lei Wang, 2015. "Occurrence and Profiles of the Artificial Endocrine Disruptor Bisphenol A and Natural Endocrine Disruptor Phytoestrogens in Urine from Children in China," IJERPH, MDPI, vol. 12(12), pages 1-8, November.
    • Handle: RePEc:gam:jijerp:v:12:y:2015:i:12:p:14964-15117:d:59602
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/12/12/14964/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/12/12/14964/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:12:y:2015:i:12:p:14964-15117:d:59602. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.