IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v12y2015i11p14285-14300d58544.html
   My bibliography  Save this article

Arsenic and Other Metals’ Presence in Biomarkers of Cambodians in Arsenic Contaminated Areas

Author

Listed:
  • Penradee Chanpiwat

    (Environmental Research Institute, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok 10330, Thailand
    Center of Excellence on Hazardous Substance Management (HSM), Chulalongkorn University, Bangkok 10330, Thailand)

  • Seiichiro Himeno

    (Department of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan)

  • Suthipong Sthiannopkao

    (Department of Environmental Engineering, College of Engineering, Dong-A University, 37 Nakdong-Daero 550 Beon-gil, Saha-gu, Busan 604-714, Korea)

Abstract

Chemical analyses of metal (Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Mo, Ba, and Pb) concentrations in hair, nails, and urine of Cambodians in arsenic-contaminated areas who consumed groundwater daily showed elevated levels in these biomarkers for most metals of toxicological interest. The levels of metals in biomarkers corresponded to their levels in groundwater, especially for As, whose concentrations exceeded the WHO guidelines for drinking water. About 75.6% of hair samples from the population in this study contained As levels higher than the normal level in unexposed individuals (1 mg·kg −1 ). Most of the population (83.3%) showed As urinary levels exceeding the normal (<50 ng·mg −1 ). These results indicate the possibility of arsenicosis symptoms in residents of the areas studied. Among the three biomarkers tested, hair has shown to be a reliable indicator of metal exposures. The levels of As ( r 2 = 0.633), Ba ( r 2 = 0.646), Fe ( r 2 = 0.595), and Mo ( r 2 = 0.555) in hair were strongly positively associated with the levels of those metals in groundwater. In addition, significant weak correlations ( p < 0.01) were found between levels of exposure to As and As concentrations in both nails ( r 2 = 0.544) and urine ( r 2 = 0.243).

Suggested Citation

  • Penradee Chanpiwat & Seiichiro Himeno & Suthipong Sthiannopkao, 2015. "Arsenic and Other Metals’ Presence in Biomarkers of Cambodians in Arsenic Contaminated Areas," IJERPH, MDPI, vol. 12(11), pages 1-16, November.
    • Handle: RePEc:gam:jijerp:v:12:y:2015:i:11:p:14285-14300:d:58544
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/12/11/14285/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/12/11/14285/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Agostino Di Ciaula & Patrizia Gentilini & Giusy Diella & Marco Lopuzzo & Ruggero Ridolfi, 2020. "Biomonitoring of Metals in Children Living in an Urban Area and Close to Waste Incinerators," IJERPH, MDPI, vol. 17(6), pages 1-17, March.
    2. Ioana Andreea Petrean & Valer Micle & Ioana Monica Sur & Marin Șenilă, 2023. "Characterization of Sterile Mining Dumps by the ICP-OES Analytical Method: A Case Study from Baia Mare Mining Area (Maramures, Romania)," Sustainability, MDPI, vol. 15(2), pages 1-14, January.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:12:y:2015:i:11:p:14285-14300:d:58544. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.