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Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)—A Randomized Controlled Lifestyle Trial

Author

Listed:
  • Tiia Ngandu

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
    Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor, SE-14157 Stockholm, Sweden)

  • Jenni Lehtisalo

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland)

  • Esko Levälahti

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland)

  • Tiina Laatikainen

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland)

  • Jaana Lindström

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland)

  • Markku Peltonen

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland)

  • Alina Solomon

    (Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor, SE-14157 Stockholm, Sweden
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland
    Aging Research Center, Karolinska Institutet—Stockholm University, Gävlegatan 16, SE-11330 Stockholm, Sweden)

  • Satu Ahtiluoto

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland)

  • Riitta Antikainen

    (Institute of Health Sciences/Geriatrics, University of Oulu, and Oulu University Hospital, P.O. Box 5000, FI-90014 University of Oulu, Finland
    Medical Research Center Oulu, Oulu University Hospital and University of Oulu, P.O. Box 5000, FI-90014 University of Oulu, Finland
    Oulu City Hospital, Kiviharjuntie 5, FI-90015 Oulu, Finland)

  • Tuomo Hänninen

    (Department of Neurology, Kuopio University Hospital, P.O. Box 100, FI-70029 KYS, Kuopio, Finland)

  • Antti Jula

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland)

  • Francesca Mangialasche

    (Aging Research Center, Karolinska Institutet—Stockholm University, Gävlegatan 16, SE-11330 Stockholm, Sweden)

  • Teemu Paajanen

    (Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FI-00250 Helsinki, Finland)

  • Satu Pajala

    (Department of Lifestyle and Participation, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland)

  • Rainer Rauramaa

    (Kuopio Research Institute of Exercise Medicine, Kuopion yliopisto, Haapaniementie 16, 70100 Kuopio, Finland)

  • Timo Strandberg

    (Institute of Health Sciences/Geriatrics, University of Oulu, and Oulu University Hospital, P.O. Box 5000, FI-90014 University of Oulu, Finland
    Department of Medicine, Geriatric Clinic, University of Helsinki, and Helsinki University Central Hospital, P.O. Box 22, FI-00014 University of Helsinki, Finland)

  • Jaakko Tuomilehto

    (Department of Public Health, University of Helsinki, P.O. Box 40, FI-00014 University of Helsinki, Finland
    South Ostrobothnia Central Hospital, Huhtalantie 53, FI-60220 Seinäjoki, Finland
    Center for Vascular Prevention, Danube-University Krems, Dr.-Karl-Dorrek-Str. 30, 3500 Krems, Austria
    Diabetes Research Group, King Abdulaziz University, P.O. Box 80200, Jeddah 21589, Saudi Arabia)

  • Hilkka Soininen

    (Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland
    Department of Neurology, Kuopio University Hospital, P.O. Box 100, FI-70029 KYS, Kuopio, Finland)

  • Miia Kivipelto

    (Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland
    Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor, SE-14157 Stockholm, Sweden
    Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland
    Aging Research Center, Karolinska Institutet—Stockholm University, Gävlegatan 16, SE-11330 Stockholm, Sweden)

Abstract

Our aim is to describe the study recruitment and baseline characteristics of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) study population. Potential study participants (age 60–77 years, the dementia risk score ≥6) were identified from previous population-based survey cohorts and invited to the screening visit. To be eligible, cognitive performance measured at the screening visit had to be at the mean level or slightly lower than expected for age. Of those invited (n = 5496), 48% (n = 2654) attended the screening visit, and finally 1260 eligible participants were randomized to the intervention and control groups (1:1). The screening visit non-attendees were slightly older, less educated, and had more vascular risk factors and diseases present. The mean (SD) age of the randomized participants was 69.4 (4.7) years, Mini-Mental State Examination 26.7 (2.0) points, systolic blood pressure 140.1 (16.2) mmHg, total serum cholesterol 5.2 (1.0) mmol/L for, and fasting glucose 6.1 (0.9) mmol/L for, with no difference between intervention and control groups. Several modifiable risk factors were present at baseline indicating an opportunity for the intervention. The FINGER study will provide important information on the effect of lifestyle intervention to prevent cognitive impairment among at risk persons.

Suggested Citation

  • Tiia Ngandu & Jenni Lehtisalo & Esko Levälahti & Tiina Laatikainen & Jaana Lindström & Markku Peltonen & Alina Solomon & Satu Ahtiluoto & Riitta Antikainen & Tuomo Hänninen & Antti Jula & Francesca Ma, 2014. "Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)—A Randomized Controlled Lifestyle Trial," IJERPH, MDPI, vol. 11(9), pages 1-16, September.
    • Handle: RePEc:gam:jijerp:v:11:y:2014:i:9:p:9345-9360:d:40069
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    Citations

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    Cited by:

    1. Susanne Röhr & Andrea Zülke & Melanie Luppa & Christian Brettschneider & Marina Weißenborn & Flora Kühne & Isabel Zöllinger & Franziska-Antonia Zora Samos & Alexander Bauer & Juliane Döhring & Kerstin, 2021. "Recruitment and Baseline Characteristics of Participants in the AgeWell.de Study—A Pragmatic Cluster-Randomized Controlled Lifestyle Trial against Cognitive Decline," IJERPH, MDPI, vol. 18(2), pages 1-15, January.
    2. HeeChel Kim & Hong-Woo Chun & Seonho Kim & Byoung-Youl Coh & Oh-Jin Kwon & Yeong-Ho Moon, 2017. "Longitudinal Study-Based Dementia Prediction for Public Health," IJERPH, MDPI, vol. 14(9), pages 1-16, August.

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