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Coronary Centerline Extraction from CCTA Using 3D-UNet

Author

Listed:
  • Alexandru Dorobanțiu

    (Computer Science and Electrical Engineering Department, Lucian Blaga University of Sibiu, 550024 Sibiu, Romania)

  • Valentin Ogrean

    (Computer Science and Electrical Engineering Department, Lucian Blaga University of Sibiu, 550024 Sibiu, Romania)

  • Remus Brad

    (Computer Science and Electrical Engineering Department, Lucian Blaga University of Sibiu, 550024 Sibiu, Romania)

Abstract

The mesh-type coronary model, obtained from three-dimensional reconstruction using the sequence of images produced by computed tomography (CT), can be used to obtain useful diagnostic information, such as extracting the projection of the lumen (planar development along an artery). In this paper, we have focused on automated coronary centerline extraction from cardiac computed tomography angiography (CCTA) proposing a 3D version of U-Net architecture, trained with a novel loss function and with augmented patches. We have obtained promising results for accuracy (between 90–95%) and overlap (between 90–94%) with various network training configurations on the data from the Rotterdam Coronary Artery Centerline Extraction benchmark. We have also demonstrated the ability of the proposed network to learn despite the huge class imbalance and sparse annotation present in the training data.

Suggested Citation

  • Alexandru Dorobanțiu & Valentin Ogrean & Remus Brad, 2021. "Coronary Centerline Extraction from CCTA Using 3D-UNet," Future Internet, MDPI, vol. 13(4), pages 1-21, April.
    • Handle: RePEc:gam:jftint:v:13:y:2021:i:4:p:101-:d:539019
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    References listed on IDEAS

    as
    1. Dongjin Han & Hackjoon Shim & Byunghwan Jeon & Yeonggul Jang & Youngtaek Hong & Sunghee Jung & Seongmin Ha & Hyuk-Jae Chang, 2016. "Automatic Coronary Artery Segmentation Using Active Search for Branches and Seemingly Disconnected Vessel Segments from Coronary CT Angiography," PLOS ONE, Public Library of Science, vol. 11(8), pages 1-24, August.
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