IDEAS home Printed from https://ideas.repec.org/a/gam/jagris/v13y2023i3p535-d1077644.html
   My bibliography  Save this article

In Vivo Hypolipidemic Effects and Antioxidant Capacity of Pinus morrisonicola Hay Extracts by Supercritical Carbon Dioxide Extraction

Author

Listed:
  • Ying-Jang Lai

    (Department of Food Science, National Quemoy University, Jinning Township, Kinmen County 892, Taiwan)

  • Ming-Ching Cheng

    (Department of Health Food, Chung Chou University of Science and Technology, Changhua 510, Taiwan)

  • Hsin-Chun Chen

    (Department of Cosmeceutics, China Medical University, Taichung 406, Taiwan)

  • Chien-Lin Chen

    (Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua 515, Taiwan)

  • Tuzz-Ying Song

    (Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua 515, Taiwan)

Abstract

Pinus morrisonicola hay (PM) is a pine tree unique to Taiwan, whose needles are used as traditional medicine and as functional drink. PME3-1 was made using supercritical extraction to evaluate the prevention of hyperlipidemia. This study explored the hypolipidemic effect of PME3-1 on hamsters on a high fat and cholesterol (HFC) diet. Three groups of hamsters were fed with PME3-1 (0.2, 1.0, and 5.0 mg/kg bw). After feeding for eight weeks, PME3-1 reduced the serum cholesterol, triglyceride levels, the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol (LDL/HDL) ratio, and the swelling of the liver and kidney significantly ( p < 0.05). In addition, feeding the hamsters with 5.0 mg/kg bw of PME3-1 could significantly reduce their total lipid (TL) content, total cholesterol (TC) content, total triglyceride (TG) content, and the HMG-CoA reductase activity in the liver ( p < 0.05). Meanwhile, the antioxidant enzymes in the liver, glutathione peroxidase (GPx) and glutathione S-transferase (GST), can also improve, promoting the excretion of triglycerides (TG) and total cholesterol (TC) in the feces ( p < 0.05). Therefore, these results confirm that PME3-1 hypolipidemic and antioxidant regulating functions in vivo .

Suggested Citation

  • Ying-Jang Lai & Ming-Ching Cheng & Hsin-Chun Chen & Chien-Lin Chen & Tuzz-Ying Song, 2023. "In Vivo Hypolipidemic Effects and Antioxidant Capacity of Pinus morrisonicola Hay Extracts by Supercritical Carbon Dioxide Extraction," Agriculture, MDPI, vol. 13(3), pages 1-13, February.
    • Handle: RePEc:gam:jagris:v:13:y:2023:i:3:p:535-:d:1077644
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/2077-0472/13/3/535/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/2077-0472/13/3/535/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jagris:v:13:y:2023:i:3:p:535-:d:1077644. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.