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Milk Thistle ( Silybum marianum ), Marine Algae ( Spirulina platensis ) and Toxin Binder Powders in the Diets of Broiler Chickens Exposed to Aflatoxin-B1: Growth Performance, Humoral Immune Response and Cecal Microbiota

Author

Listed:
  • Mostafa Feshanghchi

    (Athar Daneh Azerbijan Company, Tabriz 51386, Iran)

  • Payam Baghban-Kanani

    (Noavaran Arka Tejarat Kabodan Company, Urmia 30200, Iran)

  • Bahman Kashefi-Motlagh

    (Athar Daneh Azerbijan Company, Tabriz 51386, Iran)

  • Fariba Adib

    (Athar Daneh Azerbijan Company, Tabriz 51386, Iran)

  • Saba Azimi-Youvalari

    (Noavaran Arka Tejarat Kabodan Company, Urmia 30200, Iran)

  • Babak Hosseintabar-Ghasemabad

    (Darvash Giah Khazar Medicinal Herbs Complex, Rasht 41335, Iran)

  • Marina Slozhenkina

    (Volga Region Research Institute of Manufacture and Processing of Meat-and-Milk Production, 400131 Volgograd, Russia)

  • Ivan Gorlov

    (Volga Region Research Institute of Manufacture and Processing of Meat-and-Milk Production, 400131 Volgograd, Russia)

  • Márcio G. Zangeronimo

    (Department of Veterinary Medicine, Federal University of Lavras, Lavras 3037, Brazil)

  • Ayman A. Swelum

    (Department of Theriogenology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Sharkia, Egypt)

  • Alireza Seidavi

    (Department of Animal Science, Rasht Branch, Islamic Azad University, Rasht 41335, Iran)

  • Rifat U. Khan

    (Faculty of Animal Husbandry and Veterinary Sciences, College of Veterinary Sciences, The University of Agriculture, Peshawar 25130, Pakistan)

  • Marco Ragni

    (Department of Agro-Environmental and Territorial Sciences, University of Bari ‘Aldo Moro’, 70125 Bari, Italy)

  • Vito Laudadio

    (Department of DETO, Section of Veterinary Science and Animal Production, University of Bari ‘Aldo Moro’, 70010 Bari, Italy)

  • Vincenzo Tufarelli

    (Department of DETO, Section of Veterinary Science and Animal Production, University of Bari ‘Aldo Moro’, 70010 Bari, Italy)

Abstract

This research was performed to investigate the effects of milk thistle (MT), toxin binder (TB) and marine algae ( Spirulina platensis ; SP) on the performance, blood indices, humoral immunity and cecal microbiota of broiler chickens exposed to aflatoxin-B 1 (AFB1). A total of 300 one-day-old male chicks were equally divided into five treatments, with six replicates with 10 birds per treatment. Dietary treatments included: (T 1 ) a control diet (without any feed additive or AFB1); (T 2 ) control diet + 0.6 mg AFB 1 /kg; (T 3 ) T 2 + 10 g/kg MT; (T 4 ) T 2 + 1 g/kg TB; and (T 5 ) T 2 + 10 g/kg SP. BWG and FI were found to be considerably reduced in broilers given AFB1-contaminated diets ( p < 0.05). The FCR was negatively influenced in birds fed AFB1-contaminated diets ( p < 0.05). MT, TB, and SP powders also reduced the deleterious effects of AFB1 on the growth of chickens ( p < 0.05). In comparison with the control birds and the other treatments, broilers given AFB1-contaminated diets had a higher relative weight of abdominal fat ( p < 0.05). The feeding of AFB1 resulted in a substantial rise in AST and ALT activity ( p < 0.05). MT, TB, and SP powders significantly decreased blood AST and ALT activity in broilers ( p < 0.05). The AFB1 and MT groups had the lowest skin thickness ( p < 0.05) twenty-four hours after injection. The phytohemagglutinin injection results showed that the TB and SP were more efficient than the other additives in removing toxins from the feed sources ( p < 0.05). The antibody titer against sheep red blood cells (SRBCs) was lower in the AFB1 group compared to the control group at 28 days of age ( p < 0.05). When comparing AFB1-fed chicks to the control treatment, there was a significant ( p < 0.05) concentration of cecal Coliform bacteria. When MT, TB, and SP powders were added to AFB1-contaminated diet, cecal Coliforms were decreased ( p < 0.05). When fed AFB1-contaminated diets, it can be concluded that MT, TB, and SP are suitable for supporting growth performance, immunological function, and the serum biochemical parameters of broiler chickens.

Suggested Citation

  • Mostafa Feshanghchi & Payam Baghban-Kanani & Bahman Kashefi-Motlagh & Fariba Adib & Saba Azimi-Youvalari & Babak Hosseintabar-Ghasemabad & Marina Slozhenkina & Ivan Gorlov & Márcio G. Zangeronimo & Ay, 2022. "Milk Thistle ( Silybum marianum ), Marine Algae ( Spirulina platensis ) and Toxin Binder Powders in the Diets of Broiler Chickens Exposed to Aflatoxin-B1: Growth Performance, Humoral Immune Response a," Agriculture, MDPI, vol. 12(6), pages 1-11, June.
    • Handle: RePEc:gam:jagris:v:12:y:2022:i:6:p:805-:d:830578
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    References listed on IDEAS

    as
    1. Melissa S. Monson & Roger A. Coulombe & Kent M. Reed, 2015. "Aflatoxicosis: Lessons from Toxicity and Responses to Aflatoxin B 1 in Poultry," Agriculture, MDPI, vol. 5(3), pages 1-36, September.
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