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Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era

Author

Listed:
  • Kun Wang

    (College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
    Joint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China)

  • Qinyue Lu

    (College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
    Joint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China)

  • Xiang Cao

    (College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
    Joint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China)

  • Yuhao Wang

    (College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
    Joint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China)

  • Yanni Wu

    (College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
    Joint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China)

  • Zhi Chen

    (College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
    Joint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China)

  • Zhangping Yang

    (College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
    Joint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou 225009, China)

Abstract

Like other pentacyclic triterpenoids, oleanolic acid, a natural plant metabolite prevalent in plant peels, stems, and leaves, is regarded as a possible drug candidate. A growing number of studies have shown that oleanolic acid exhibits a variety of beneficial properties, including antiviral, anti-inflammatory, antioxidant, anticancer, and hepatoprotective effects. Additionally, the rapid advance of nanotechnology has dramatically improved oleanolic acid’s bioavailability and minimized its disadvantages, leading to unexpected changes in its pharmacological activity and use. Therefore, our aim was to review the progress of research on the distribution and biological properties of oleanolic acid in plants and to discuss new pharmaceutical approaches for oleanolic acid.

Suggested Citation

  • Kun Wang & Qinyue Lu & Xiang Cao & Yuhao Wang & Yanni Wu & Zhi Chen & Zhangping Yang, 2022. "Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era," Agriculture, MDPI, vol. 12(12), pages 1-21, December.
    • Handle: RePEc:gam:jagris:v:12:y:2022:i:12:p:2142-:d:1001983
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    Cited by:

    1. Yong Sun & Hui Liu & Jiwei Liu & Mingyu Sun & Qun Li, 2023. "Analysis of Factors Influencing the Corporate Performance of Listed Companies in China’s Agriculture and Forestry Sector Based on a Panel Threshold Model," Sustainability, MDPI, vol. 15(2), pages 1-21, January.

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