IDEAS home Printed from https://ideas.repec.org/a/eee/stapro/v56y2002i2p207-216.html
   My bibliography  Save this article

Testing against ordered alternatives for multivariate censored survival data

Author

Listed:
  • Dubnicka, Suzanne R.

Abstract

In clinical trials where the treatment groups correspond to increasing dosages of a substance and the outcome is the possibly right-censored time to a certain event, it is desirable to test for increases or decreases in survival times with increasing dose. Furthermore, it may be of interest to study several endpoints simultaneously. Two asymptotically distribution-free tests are considered: one to test the alternative hypothesis that the survival times are stochastically increasing with increasing dose and another to test the alternative that the survival times are stochastically ordered (either increasing or decreasing) with increasing dose. An important special case concerns the general problem of testing for ordered alternatives with incomplete multivariate (repeated measures) data.

Suggested Citation

  • Dubnicka, Suzanne R., 2002. "Testing against ordered alternatives for multivariate censored survival data," Statistics & Probability Letters, Elsevier, vol. 56(2), pages 207-216, January.
    • Handle: RePEc:eee:stapro:v:56:y:2002:i:2:p:207-216
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167-7152(01)00189-4
    Download Restriction: Full text for ScienceDirect subscribers only
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:stapro:v:56:y:2002:i:2:p:207-216. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/wps/find/journaldescription.cws_home/622892/description#description .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.