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Determinants for the adoption of angiotensin II receptor blockers by general practitioners

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Listed:
  • Greving, Jacoba P.
  • Denig, Petra
  • van der Veen, Willem Jan
  • Beltman, Frank W.
  • Sturkenboom, Miriam C.J.M.
  • Haaijer-Ruskamp, Flora M.

Abstract

Results of studies conducted 10-20 years ago show the prominence of commercial information sources in the adoption process of new drugs. Over the past decade, there has been a growing emphasis on practicing evidence-based medicine in drug prescribing. This raises the question whether professional information sources currently counterbalance the influence of commercial information sources in the adoption process. The aim of this study was to identify determinants influencing the adoption of a new drug class, the angiotensin II receptor blockers (ARBs), by general practitioners (GPs) in The Netherlands. A retrospective study was conducted to assess prevalent ARB prescribing for hypertensive patients using the Integrated Primary Care Information (IPCI) database. We conducted a survey among all GPs who participated in the IPCI project in 2003 to assess their exposure to commercial and professional information sources, perceived benefits and risks of ARBs, perceived influences of the professional network, and general characteristics. Multilevel logistic regression was applied to identify determinants of ARB adoption while adjusting for patient characteristics. Data were obtained from 70 GPs and 9470 treated hypertensive patients. A total of 1093 patients received ARBs (12%). GPs who reported frequent use of commercial information sources were more likely to prescribe ARBs routinely in preference to other antihypertensives, whereas GPs who used a prescribing decision support system and those who were involved in pharmacotherapy education were less likely to prescribe ARBs. Other factors that were associated with higher levels of ARB adoption included a more positive perception of ARBs regarding their effectiveness in lowering blood pressure, and working in single-handed practices or in rural areas. Aside from determinants related to the patient population, adoption of a new drug class among Dutch GPs is still determined more by their reliance on promotional information than by their use of professional information sources.

Suggested Citation

  • Greving, Jacoba P. & Denig, Petra & van der Veen, Willem Jan & Beltman, Frank W. & Sturkenboom, Miriam C.J.M. & Haaijer-Ruskamp, Flora M., 2006. "Determinants for the adoption of angiotensin II receptor blockers by general practitioners," Social Science & Medicine, Elsevier, vol. 63(11), pages 2890-2898, December.
    • Handle: RePEc:eee:socmed:v:63:y:2006:i:11:p:2890-2898
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    References listed on IDEAS

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    1. Denig, P. & Haaijer-Ruskamp, F.M. & Zijsling, D.H., 1988. "How physicians choose drugs," Social Science & Medicine, Elsevier, vol. 27(12), pages 1381-1386, January.
    2. Peay, Marilyn Y. & Peay, Edmund R., 1984. "Differences among practitioners in patterns of preference for information sources in the adoption of new drugs," Social Science & Medicine, Elsevier, vol. 18(12), pages 1019-1025, January.
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    1. Bence Kovács & Miklós Darida & Judit Simon, 2021. "Drugs Becoming Generics—The Impact of Genericization on the Market Performance of Antihypertensive Active Pharmaceutical Ingredients," IJERPH, MDPI, vol. 18(18), pages 1-20, September.
    2. Monteiro, Carlos M.F. & Dibb, Sally & Almeida, Luis Tadeu, 2010. "Revealing doctors' prescribing choice dimensions with multivariate tools: A perceptual mapping approach," European Journal of Operational Research, Elsevier, vol. 201(3), pages 909-920, March.
    3. Ronja Flemming & Franziska Frölich & Norbert Donner‐Banzhoff & Leonie Sundmacher, 2023. "Diffusion of a new drug among ambulatory physicians—The impact of patient pathways," Health Economics, John Wiley & Sons, Ltd., vol. 32(4), pages 970-982, April.

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