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The effect of executive function on the development of chronic pain: A prospective longitudinal study

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  • Ng, Wee Qin
  • Hartanto, Andree

Abstract

Increasing evidence suggests a close association between chronic pain and executive function, a set of cognitive processes necessary for goal-directed behaviors. However, there is a dearth of longitudinal studies examining the predictive effect of executive function on the development of chronic pain. Drawing on the cyclical model of executive function and health, we sought to examine how executive function, measured at baseline, may predict chronic pain etiology approximately 9 years later. Using a large-scale dataset of midlife adults (N = 1553) from the MIDUS 2 and 3 (Midlife Development in the United States) studies, we employed multivariate logistic regression to examine the etiology of new chronic pain for individuals who did not have chronic pain at baseline. Further, we also tested whether executive function predicted the degree of pain interference, among individuals with chronic pain. Our results revealed that lower baseline executive function was associated with a significant likelihood of developing chronic pain 9 years later (OR = 0.812, p = .001), even after adjusting for demographics, health, and psychosocial confounds (OR = 0.827, p = .014). However, executive function failed to robustly predict the etiology and degree of chronic pain interference. Our findings underscore the critical role of executive function on the development of chronic pain.

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  • Ng, Wee Qin & Hartanto, Andree, 2022. "The effect of executive function on the development of chronic pain: A prospective longitudinal study," Social Science & Medicine, Elsevier, vol. 314(C).
    • Handle: RePEc:eee:socmed:v:314:y:2022:i:c:s0277953622007845
    DOI: 10.1016/j.socscimed.2022.115478
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    References listed on IDEAS

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    1. Tormod Landmark & Pål R Romundstad & Petter C Borchgrevink & Stein Kaasa & Ola Dale, 2013. "Longitudinal Associations between Exercise and Pain in the General Population - The HUNT Pain Study," PLOS ONE, Public Library of Science, vol. 8(6), pages 1-6, June.
    2. Brown, Timothy T. & Partanen, Juulia & Chuong, Linh & Villaverde, Vaughn & Chantal Griffin, Ann & Mendelson, Aaron, 2018. "Discrimination hurts: The effect of discrimination on the development of chronic pain," Social Science & Medicine, Elsevier, vol. 204(C), pages 1-8.
    3. Luís Azevedo & Altamiro Costa-Pereira & Liliane Mendonça & Cláudia Dias & José Castro-Lopes, 2016. "The economic impact of chronic pain: a nationwide population-based cost-of-illness study in Portugal," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 17(1), pages 87-98, January.
    4. Woods, Sarah B. & Priest, Jacob B. & Kuhn, Veronica & Signs, Tara, 2019. "Close relationships as a contributor to chronic pain pathogenesis: Predicting pain etiology and persistence," Social Science & Medicine, Elsevier, vol. 237(C), pages 1-1.
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    Cited by:

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