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Population genetic models in the study of aging and longevity in a mennonite community

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  • Crawford, M. H.
  • Rogers, L.

Abstract

This is a preliminary report on a 3-year multidisciplinary study of aging among historically and genetically related Mennonite congregations in Kansas and Nebraska. Three aspects of longevity and aging are examined: (1) the relationship of heterozygosity to survivorship using 8 genetic blood group loci, (2) changes in taste sensitivity with age using 14 dilutions of PTC; and (3) life span correlations among parents and offspring during a 100 year period. Heterozygosity was found to be independent of survivorship. No diminution in taste sensitivity to PTC was found with increasing age although a significant difference in PTC taste thresholds was found between males and females. No relationship was found between nontasters and individuals with a history of thyroid disease. Mother's life span was found to correlate more closely with daughter than any other familial correlation.

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  • Crawford, M. H. & Rogers, L., 1982. "Population genetic models in the study of aging and longevity in a mennonite community," Social Science & Medicine, Elsevier, vol. 16(2), pages 149-153, January.
    • Handle: RePEc:eee:socmed:v:16:y:1982:i:2:p:149-153
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    Cited by:

    1. James Vaupel, 1988. "Inherited frailty and longevity," Demography, Springer;Population Association of America (PAA), vol. 25(2), pages 277-287, May.
    2. Graziella Caselli & Rosa Maria Lipsi & Enrica Lapucci & James W. Vaupel, 2013. "Exploring Sardinian longevity: women fertility and parental transmission of longevity," Vienna Yearbook of Population Research, Vienna Institute of Demography (VID) of the Austrian Academy of Sciences in Vienna, vol. 11(1), pages 247-266.

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