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Irreversibility indices as discriminators of heart conditions from Electrocardiographic signals

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  • Maldonado, Cesar
  • Merino–Negrete, Nazul

Abstract

We estimate the entropy production rate and the Kullback–Leibler divergence in discrete time series of electrocardiographic and the RR-interval signals of healthy and unhealthy patients. We show that these indices of irreversibility, applied directly to the electrocardiographic signals, may be used as a tool for discrimination between healthy subjects and patients with heart conditions. We test our method in a controlled Markov chain model. Finally, we test the performance of our methodology of discrimination by quantifying its accuracy using ROC analysis.

Suggested Citation

  • Maldonado, Cesar & Merino–Negrete, Nazul, 2024. "Irreversibility indices as discriminators of heart conditions from Electrocardiographic signals," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 637(C).
    • Handle: RePEc:eee:phsmap:v:637:y:2024:i:c:s037843712400092x
    DOI: 10.1016/j.physa.2024.129584
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    References listed on IDEAS

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    1. Cammarota, Camillo & Rogora, Enrico, 2007. "Time reversal, symbolic series and irreversibility of human heartbeat," Chaos, Solitons & Fractals, Elsevier, vol. 32(5), pages 1649-1654.
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