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Complex network model of the Treatise on Cold Damage Disorders

Author

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  • Shao, Feng-jing
  • Sui, Yi
  • Zhou, Yong-hong
  • Sun, Ren-cheng

Abstract

Investigating the underlying principles of the Treatise on Cold Damage Disorder is meaningful and interesting. In this study, we investigated the symptoms, herbal formulae, herbal drugs, and their relationships in this treatise based on a multi-subnet composited complex network model (MCCN). Syndrome subnets were constructed for the symptoms and a formula subnet for herbal drugs. By subnet compounding using MCCN, a composited network was obtained that described the treatment relationships between syndromes and formulae. The results obtained by topological analysis suggested some prescription laws that could be validated in clinics. After subnet reduction using the MCCN, six channel (Tai-yang, Yang-ming, Shao-yang, Tai-yin, Shao-yin, and Jue-yin) subnets were obtained. By analyzing the strengths of the relationships among these six channel subnets, we found that the Tai-yang channel and Yang-ming channel were related most strongly with each other, and we found symptoms that implied pathogen movements and transformations among the six channels. This study could help therapists to obtain a deeper understanding of this ancient treatise.

Suggested Citation

  • Shao, Feng-jing & Sui, Yi & Zhou, Yong-hong & Sun, Ren-cheng, 2016. "Complex network model of the Treatise on Cold Damage Disorders," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 460(C), pages 152-161.
  • Handle: RePEc:eee:phsmap:v:460:y:2016:i:c:p:152-161
    DOI: 10.1016/j.physa.2016.03.115
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    References listed on IDEAS

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    1. Fengjing Shao & Yi Sui, 2014. "Reorganizations of complex networks: Compounding and reducing," International Journal of Modern Physics C (IJMPC), World Scientific Publishing Co. Pte. Ltd., vol. 25(05), pages 1-11.
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    Cited by:

    1. Matsuzawa, Ryo & Tanimoto, Jun & Fukuda, Eriko, 2017. "Properties of a new small-world network with spatially biased random shortcuts," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 486(C), pages 408-415.

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