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In silico study on the effects of matrix structure in controlled drug release

Author

Listed:
  • Villalobos, Rafael
  • Cordero, Salomón
  • Maria Vidales, Ana
  • Domínguez, Armando

Abstract

Purpose: To study the effects of drug concentration and spatial distribution of the medicament, in porous solid dosage forms, on the kinetics and total yield of drug release.

Suggested Citation

  • Villalobos, Rafael & Cordero, Salomón & Maria Vidales, Ana & Domínguez, Armando, 2006. "In silico study on the effects of matrix structure in controlled drug release," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 367(C), pages 305-318.
    • Handle: RePEc:eee:phsmap:v:367:y:2006:i:c:p:305-318
    DOI: 10.1016/j.physa.2005.11.009
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    Citations

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    Cited by:

    1. Singh, Kulveer & Satapathi, Soumitra & Jha, Prateek K., 2019. "“Ant-Wall” model to study drug release from excipient matrix," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 519(C), pages 98-108.
    2. Ignacio, Maxime & Chubynsky, Mykyta V. & Slater, Gary W., 2017. "Interpreting the Weibull fitting parameters for diffusion-controlled release data," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 486(C), pages 486-496.
    3. Villalobos, Rafael & Domínguez, Armando & Ganem, Adriana & Vidales, Ana Maria & Cordero, Salomón, 2009. "One-dimensional drug release from finite Menger sponges: In silico simulation," Chaos, Solitons & Fractals, Elsevier, vol. 42(5), pages 2875-2884.
    4. Gomes Filho, Márcio Sampaio & Oliveira, Fernando Albuquerque & Barbosa, Marco Aurélio Alves, 2016. "A statistical mechanical model for drug release: Investigations on size and porosity dependence," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 460(C), pages 29-37.
    5. Gomes-Filho, Márcio Sampaio & Barbosa, Marco Aurélio Alves & Oliveira, Fernando Albuquerque, 2020. "A statistical mechanical model for drug release: Relations between release parameters and porosity," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 540(C).

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