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Driven translocation dynamics of polynucleotides through a nanopore: off-lattice Monte-Carlo simulations

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  • Chen, C.-M.

Abstract

The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.

Suggested Citation

  • Chen, C.-M., 2005. "Driven translocation dynamics of polynucleotides through a nanopore: off-lattice Monte-Carlo simulations," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 350(1), pages 95-107.
    • Handle: RePEc:eee:phsmap:v:350:y:2005:i:1:p:95-107
    DOI: 10.1016/j.physa.2004.11.026
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    References listed on IDEAS

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    1. Chang, Fwu-Ranq, 2004. "Life insurance, precautionary saving and contingent bequest," Mathematical Social Sciences, Elsevier, vol. 48(1), pages 55-67, July.
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