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Numerical investigation of acoustic droplet vaporization and tissue deformation

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  • Park, Jaesung
  • Son, Gihun

Abstract

Acoustically-triggered droplet vaporization (ADV) and tissue deformation are numerically analyzed by extending a numerical model for ADV process based on a level-set method, which considers multiple interfaces between bubble, droplet and ambient water regions, bubble compressibility and droplet-bubble phase change, to include nearby tissue deformation using a full Eulerian formulation. The tissue is assumed to be a viscoelastic neo-Hookean material to properly handle large deformation. The numerical results show that droplet vaporization causes greater tissue deformation than isothermal bubble growth under the same acoustic and initial size conditions. The computations of ADV near a deformable solid demonstrate various bubble-tissue interactions such as mushroom-shaped bubble formation near an elastic tissue, tissue compression due to high-speed liquid jet, and large tissue deformation and perforation caused by the non-spherical bubble re-expansion and bubble entrapment. The effects of droplet-tissue distance and elastic shear modulus on the tissue deformation and perforation are investigated.

Suggested Citation

  • Park, Jaesung & Son, Gihun, 2024. "Numerical investigation of acoustic droplet vaporization and tissue deformation," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 225(C), pages 412-429.
  • Handle: RePEc:eee:matcom:v:225:y:2024:i:c:p:412-429
    DOI: 10.1016/j.matcom.2024.05.030
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    1. Zakaria, Mohamad Shukri & Ismail, Farzad & Tamagawa, Masaaki & Aziz, Ahmad Fazli Abdul & Wiriadidjaja, Surjatin & Basri, Adi Azrif & Ahmad, Kamarul Arifin, 2019. "A Cartesian non-boundary fitted grid method on complex geometries and its application to the blood flow in the aorta using OpenFOAM," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 159(C), pages 220-250.
    2. Ghosh, Sudeshna, 2021. "Immersed boundary simulations of fluid shear-induced deformation of a cantilever beam," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 185(C), pages 384-402.
    3. Chrispell, J.C. & Jenkins, E.W. & Westerbaan, P., 2021. "Simulation of ratcheting non-Newtonian fluids using a geometric anisotropy," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 188(C), pages 436-454.
    4. Tao, Liang & Deng, Xiao-Long, 2020. "A new and improved cut-cell-based sharp-interface method for simulating compressible fluid elastic–perfectly plastic solid interaction," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 171(C), pages 246-263.
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