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Accuracy of simple difference-differential equations for blood flow in arteries

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  • Lefevre, J.
  • Magnus, A.

Abstract

This paper presents an analysis of the numerical accuracy of the representation of an arterial segment by difference-differential equations (dde) of low order (N). The analysis is done by comparing, in the linear autonomous case, the two-port representations of the exact solution (Womersley) and of the lumped approximation (Rideout) of the flow by N annuli of constant flows. For low N (2, 3) it is shown that the dde's overestimate greatly the longitudinal impedance of the artery. For higher N, we give a closed-form expression for this longitudinal impedance approximation and show that it converges toward the Womersley solution for N → ∞. However for N ⩽ 5 (which are the only practical cases) the error in longitudinal impedance remains large. Finally, the practical influence of these errors, is shown on a model of the pulmonary vascular bed of the dog for which the use of Rideout's method completely destroys the input impedance pattern shown by the Womersley solution.

Suggested Citation

  • Lefevre, J. & Magnus, A., 1979. "Accuracy of simple difference-differential equations for blood flow in arteries," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 21(4), pages 340-351.
  • Handle: RePEc:eee:matcom:v:21:y:1979:i:4:p:340-351
    DOI: 10.1016/0378-4754(79)90003-X
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    1. Rideout, V.C. & Beneken, J.E.W., 1975. "Parameter estimation applied to physiological systems," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 17(1), pages 23-36.
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