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Cell-to-cell mathematical modeling of arrhythmia phenomena in the heart

Author

Listed:
  • López Garza, Gabriel
  • Nicolás Mata, Aurelio
  • Román Alonso, Graciela
  • Godínez Fernández, José Rafael
  • Castro García, Miguel Alfonso

Abstract

In this work, we investigate deterministic mechanisms that generate and perpetuate flutter and fibrillation in the right atrium of the human heart using mathematical models and high-performance computational simulations. Using a GPU, the solutions of systems of as much as 360 000 cells of 29 variables each were distributed among the available processors to simulate a cell-to-cell electric behavior of heart tissue.

Suggested Citation

  • López Garza, Gabriel & Nicolás Mata, Aurelio & Román Alonso, Graciela & Godínez Fernández, José Rafael & Castro García, Miguel Alfonso, 2022. "Cell-to-cell mathematical modeling of arrhythmia phenomena in the heart," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 193(C), pages 153-172.
  • Handle: RePEc:eee:matcom:v:193:y:2022:i:c:p:153-172
    DOI: 10.1016/j.matcom.2021.10.002
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    Cited by:

    1. Smidtaite, Rasa & Ragulskis, Minvydas, 2022. "Spiral waves of divergence in the Barkley model of nilpotent matrices," Chaos, Solitons & Fractals, Elsevier, vol. 159(C).

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