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Financial payments made by pharmaceutical companies to the authors of Japanese hematology clinical practice guidelines between 2016 and 2017

Author

Listed:
  • Harada, Kayo
  • Ozaki, Akihiko
  • Saito, Hiroaki
  • Sawano, Toyoaki
  • Yamamoto, Kana
  • Murayama, Anju
  • Senoo, Yuki
  • Tanimoto, Tetsuya

Abstract

Financial conflicts of interest (FCOI) between pharmaceutical companies and physicians may negatively impact patient care. This is particularly relevant regarding clinical practice guidelines (CPG), where FCOI may inappropriately influence individual drugs' promotion or use. In a cross-sectional analysis of pharmaceutical company payments, we sought to elucidate the extent of FCOI between Japanese hematologists and drug promotion in CPG. Data collected from two professional medical associations and companies belonging to the Japanese Pharmaceutical Manufacturers Association included the type and amount of company payments, individual financial disclosures, and new drug or indication approvals between 2015 and 2017. Of the 74 hematologists drafting CPG, 70 (94.6 %) received at least one payment during the study period. The cumulative median (interquartile range) value of these payments was $31,553 ($11,449-$74,390). Also, during this period, 26 new drugs or indications were approved and discussed in the CPG. Among the 79 pharmaceutical companies, the 11 (13.9 %) with newly approved and discussed drugs in the CPG made median (interquartile range) payments of $210,388 ($85,141-$292,536), while the remaining 68 (86.1 %) made $0 ($0-$9607) in payments. Disclosure of these payments was inconsistent. Such discrepancies suggest an association between pharmaceutical payments and drug approvals that only greater transparency can clarify. Consequently, a comprehensive overhaul of the current framework to control FCOI that includes legal regulation may be necessary.

Suggested Citation

  • Harada, Kayo & Ozaki, Akihiko & Saito, Hiroaki & Sawano, Toyoaki & Yamamoto, Kana & Murayama, Anju & Senoo, Yuki & Tanimoto, Tetsuya, 2021. "Financial payments made by pharmaceutical companies to the authors of Japanese hematology clinical practice guidelines between 2016 and 2017," Health Policy, Elsevier, vol. 125(3), pages 320-326.
  • Handle: RePEc:eee:hepoli:v:125:y:2021:i:3:p:320-326
    DOI: 10.1016/j.healthpol.2020.12.005
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    References listed on IDEAS

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    1. Anju Murayama & Akihiko Ozaki & Hiroaki Saito & Toyoaki Sawano & Yuki Shimada & Kana Yamamoto & Yosuke Suzuki & Tetsuya Tanimoto, 2020. "Pharmaceutical company payments to dermatology Clinical Practice Guideline authors in Japan," PLOS ONE, Public Library of Science, vol. 15(10), pages 1-16, October.
    2. Ozaki, Akihiko & Saito, Hiroaki & Senoo, Yuki & Sawano, Toyoaki & Shimada, Yuki & Kobashi, Yurie & Yamamoto, Kana & Suzuki, Yosuke & Tanimoto, Tetsuya, 2020. "Overview and transparency of non-research payments to healthcare organizations and healthcare professionals from pharmaceutical companies in Japan: Analysis of payment data in 2016," Health Policy, Elsevier, vol. 124(7), pages 727-735.
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