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Are public-private partnerships the solution to tackle neglected tropical diseases? A systematic review of the literature

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  • Aerts, Céline
  • Sunyoto, Temmy
  • Tediosi, Fabrizio
  • Sicuri, Elisa

Abstract

Pharmaceutical companies are reluctant to invest in research and development (R&D) of products for neglected tropical diseases (NTDs) mainly due to the low ability-to-pay of health insurance systems and of potential consumers. The available preventive and curative interventions for NTDs mostly rely on old technologies and products that are often not adequate. Moreover, NTDs mostly affect populations living in remote rural areas and conflict zones, thereby hampering access to healthcare. The challenges posed by NTDs have led to the proliferation of a variety of public-private partnerships (PPPs) in the last decades. We conducted a systematic review to assess the functioning and impact of these partnerships on the development of and access to better technologies for NTDs. Our systematic review revealed a clear lack of empirical assessment of PPPs: we could not find any impact evaluation analyses, while these are crucial to realize the full potential of PPPs and to progress further towards NTDs elimination.

Suggested Citation

  • Aerts, Céline & Sunyoto, Temmy & Tediosi, Fabrizio & Sicuri, Elisa, 2017. "Are public-private partnerships the solution to tackle neglected tropical diseases? A systematic review of the literature," Health Policy, Elsevier, vol. 121(7), pages 745-754.
    • Handle: RePEc:eee:hepoli:v:121:y:2017:i:7:p:745-754
    DOI: 10.1016/j.healthpol.2017.05.005
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    References listed on IDEAS

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    1. Jimmy Le, 2014. "Financing Sustainable Drug Development for Neglected Diseases: A Case of Push-Pull Mechanisms and Global Public Goods," The Economic and Social Review, Economic and Social Studies, vol. 45(2), pages 245-259.
    2. Mrazek, Monique F. & Mossialos, Elias, 2003. "Stimulating pharmaceutical research and development for neglected diseases," Health Policy, Elsevier, vol. 64(1), pages 75-88, April.
    3. Pratt, B. & Loff, B., 2013. "Linking research to global health equity: The contribution of product development partnerships to access to medicines and research capacity building," American Journal of Public Health, American Public Health Association, vol. 103(11), pages 1968-1978.
    4. De Pinho Campos, Katia & Norman, Cameron D. & Jadad, Alejandro R., 2011. "Product development public–private partnerships for public health: A systematic review using qualitative data," Social Science & Medicine, Elsevier, vol. 73(7), pages 986-994.
    5. R. L. Juliano, 2013. "Pharmaceutical innovation and public policy: The case for a new strategy for drug discovery and development," Science and Public Policy, Oxford University Press, vol. 40(3), pages 393-405, February.
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    1. Nannan Wang & Minxun Ma, 2021. "Public–private partnership as a tool for sustainable development – What literatures say?," Sustainable Development, John Wiley & Sons, Ltd., vol. 29(1), pages 243-258, January.
    2. Perez, Marybel & von Schnurbein, Georg & Gehringer, Theresa, 2022. "Mitigating health policy fragmentation through interlocks. The networks between American and Swiss public-private partnerships," Health Policy, Elsevier, vol. 126(11), pages 1163-1172.

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