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Localized transient conduction block to suppress and eliminate spiral wave doppler instability: A numerical simulation study

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  • Xu, Hongling
  • Wu, Weibang
  • Pan, Debei

Abstract

Atrial fibrillation (AF) is a common cardiac arrhythmia associated with spiral wave Doppler instability. Current ablation strategies in clinical practice primarily aim to isolate wave propagation and prevent the formation and maintenance of re-entrant waves. In this study, we investigate the effects of targeted localized transient conduction blocks on controlling spiral wave Doppler instability in a maximally simplified, homogeneous model. Numerical simulations reveal that spiral waves approaching Doppler instability can be effectively anchored by introducing localized conduction blocks near their rotational centers, thereby suppressing spiral tips instability. Subsequently, the spiral waves can be guided to and eliminated at the nearest non-conducting boundaries. The effects of conduction block size, movement speed, and direction on spiral wave anchoring and elimination are systematically analyzed and evaluated. Moreover, the proposed approach is applicable in scenarios with multiple coexisting spiral wavelets within a medium. These findings provide valuable insights into the mechanisms of localized conduction block and offer a foundation for exploring potential strategies or methods to control spiral wave dynamics in excitable media.

Suggested Citation

  • Xu, Hongling & Wu, Weibang & Pan, Debei, 2025. "Localized transient conduction block to suppress and eliminate spiral wave doppler instability: A numerical simulation study," Chaos, Solitons & Fractals, Elsevier, vol. 193(C).
    • Handle: RePEc:eee:chsofr:v:193:y:2025:i:c:s0960077925001535
    DOI: 10.1016/j.chaos.2025.116140
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