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Effects of praziquantel on early life stages of Grass carp, Ctenopharyngodon idella

Author

Listed:
  • J Velisek

    (South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Vodnany, Czech Republic)

  • A Strouhova

    (South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Vodnany, Czech Republic)

  • M Sandova

    (South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Vodnany, Czech Republic)

  • E Zuskova

    (South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Vodnany, Czech Republic)

  • P Dvorak

    (South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Vodnany, Czech Republic)

  • A Stara

    (South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Vodnany, Czech Republic)

Abstract

This study aimed to assess the toxicity of the anthelmintic drug praziquantel in the early life stages of grass carp (Ctenopharyngodon idella). The toxicity was evaluated based on mortality, early ontogeny development, growth, oxidative stress biomarkers, antioxidant enzymes and histopathology. Praziquantel at all tested concentrations (1, 2, 4 and 6 mg/l) showed no significant adverse effects on the hatching of grass carp. Concentrations of 2, 4 and 6 mg/l praziquantel caused significantly (P < 0.01) higher mortality and slower growth compared with controls. Praziquantel at concentrations (4 and 6 mg/l) showed a significant (P < 0.01) delay of early ontogeny of grass carp. Concentration of 2 mg/l praziquantel caused significantly (P < 0.01) higher GST activity than controls. Among the groups, no histological changes were detected in tissues. For the early life of grass carp, praziquantel is safe at concentrations ≤1 mg/l.

Suggested Citation

  • J Velisek & A Strouhova & M Sandova & E Zuskova & P Dvorak & A Stara, 2025. "Effects of praziquantel on early life stages of Grass carp, Ctenopharyngodon idella," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 70(3), pages 93-100.
    • Handle: RePEc:caa:jnlvet:v:70:y:2025:i:3:id:85-2024-vetmed
    DOI: 10.17221/85/2024-VETMED
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    References listed on IDEAS

    as
    1. E Zuskova & V Piackova & O Valentova & K Zalohova & J Velisek, 2022. "Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 67(11), pages 579-584.
    2. J Kolarova & E Zuskova & J Velisek, 2022. "Efficacy of a therapeutic bath with selected antiparasitic drugs on a Dactylogyrus anchoratus infection in juvenile common carp (Cyprinus carpio)," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 67(12), pages 620-627.
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