IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v69y2024i8id19-2024-vetmed.html
   My bibliography  Save this article

Non-surgical pain management for hip joint disease in veterinary medicine

Author

Listed:
  • J Toholova

    (Small Animal Clinic, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic)

  • S Hornak

    (Small Animal Clinic, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic)

  • M Kuricova

    (Small Animal Clinic, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic)

Abstract

The most common orthopaedic developmental disease in dogs is hip dysplasia. This condition results in coxofemoral laxity due to incongruity and lack of stabilisation of the joint by the soft tissues. Currently, there is no therapeutic plan to correct hip dysplasia without surgical intervention at a very early age. The goal of the non-surgical treatment is to relieve pain and stiffness and to increase the muscle strength, usually through hydrotherapy and the beneficial physical properties of water. Recently, there has been growing interest in regenerative medicine, which involves the use of mesenchymal stem cells (MSCs) and their products to alleviate the characteristic clinical symptoms of osteoarthritis (OA). In vivo studies with canine MSCs have shown that an intra-articular injection of MSCs into cartilage lesions leads to the excellent regeneration of the hyaline cartilage. Regenerative medicine has undergone rapid development in recent years thanks to new therapies based on the application and combination of innovative biomaterials. One of the first known regenerative methods to be used in clinical practice was platelet-rich plasma (PRP). This review summarises the use and potential of MSCs and PRP, including their in vitro properties, their therapeutic effects in the treatment of cartilage lesions in preclinical in vivo studies, their clinical efficacy in the treatment of naturally occurring OA in dogs, and the current limitations of the studies.

Suggested Citation

  • J Toholova & S Hornak & M Kuricova, 2024. "Non-surgical pain management for hip joint disease in veterinary medicine," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 69(8), pages 261-272.
  • Handle: RePEc:caa:jnlvet:v:69:y:2024:i:8:id:19-2024-vetmed
    DOI: 10.17221/19/2024-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/19/2024-VETMED.html
    Download Restriction: free of charge

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/19/2024-VETMED.pdf
    Download Restriction: free of charge

    File URL: https://libkey.io/10.17221/19/2024-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:69:y:2024:i:8:id:19-2024-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.