IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v69y2024i11id15-2024-vetmed.html
   My bibliography  Save this article

A novel pigeon paramyxovirus type 1 isolated from a sick racing pigeon in the Qinghai-Tibet Plateau of China shows high virulence in chickens

Author

Listed:
  • L Tong

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

  • X Gao

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

  • L Feng

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

  • D Yao

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

  • X Zhang

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

  • Y Du

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

  • Y Zhou

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

  • F Chen

    (College of Agriculture and Animal Husbandry, Qinghai University, Xining, P.R. China)

Abstract

Pigeon paramyxovirus type-1 (PPMV-1) is the causative agent of pigeon Newcastle disease (ND), which has caused huge losses to the pigeon industry. In this study, a PPMV-1 strain, PPMV-1/QH-01/CH/23, was isolated from a sick racing pigeon in the Qinghai-Tibet Plateau, China in 2023. The mean death time of chicken embryos and the intracerebral pathogenicity index (ICPI) were 76.8 h and 1.25, indicating a mesogenic strain. Pigeon morbidity and mortality were 100% and 80%, respectively, and both were 80% in chickens; therefore, this isolate was velogenic for both pigeons and chickens. The fusion gene was amplified and sequenced for phylogenetic analysis, and the results indicated that the isolated strain possessed a virulent fusion protein cleavage site motif, 112R-R-Q-K-R-F117, and belonged to genotype XX (former sub-genotype VIc) of class II; this was different from the predominant sub-genotype, VI.2.1.1.2.2, which is prevalent in pigeons. To the best of our knowledge, this is the first report of a novel genotype XX isolate possessing high virulence for both chickens and pigeons in the Qinghai-Tibet Plateau, China.

Suggested Citation

  • L Tong & X Gao & L Feng & D Yao & X Zhang & Y Du & Y Zhou & F Chen, 2024. "A novel pigeon paramyxovirus type 1 isolated from a sick racing pigeon in the Qinghai-Tibet Plateau of China shows high virulence in chickens," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 69(11), pages 389-394.
    • Handle: RePEc:caa:jnlvet:v:69:y:2024:i:11:id:15-2024-vetmed
    DOI: 10.17221/15/2024-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/15/2024-VETMED.html
    Download Restriction: free of charge
    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/15/2024-VETMED.pdf
    Download Restriction: free of charge
    File URL: https://libkey.io/10.17221/15/2024-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:69:y:2024:i:11:id:15-2024-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.