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Successful management of feline CD4+ CD8+ T-cell mediastinal lymphoma with pericardial effusion

Author

Listed:
  • SJ Yu

    (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Gwangjin-gu, Seoul, Republic of Korea)

  • HE Kim

    (Department of Veterinary Internal Medicine, Konkuk University Veterinary Medical Teaching Hospital, Gwangjin-gu, Seoul, Republic of Korea)

  • HJ Han

    (Veterinary Emergency Medicine and Critical Care, Konkuk University Veterinary Medical Teaching Hospital, Gwangjin-gu, Seoul, Republic of Korea)

  • JH Kim

    (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Gwangjin-gu, Seoul, Republic of Korea)

Abstract

A 2-year-old, castrated, male Russian blue cat presented with acute dyspnoea, cyanosis, and lethargy. A thoracic radiography revealed a large cranial mediastinal mass; the computed tomography revealed caudal lobe atelectasis of the right lung with pericardial and pleural effusions. The cytodiagnostic tests revealed high-grade CD4+ CD8+ T-cell mediastinal lymphoma as clinical stage Vb; l-asparaginase-cyclophosphamide-doxorubicin-vincristine-prednisolone (l-CHOP)-based chemotherapy was initiated, following which the mass shrunk rapidly; 1 week after the initiation of chemotherapy, the appetite-related and respiratory symptoms improved dramatically, and the pleural and pericardial effusion resolved. The patient remains in complete remission three years after the initiation of the l-CHOP chemotherapy. Therefore, the accurate diagnosis and instantaneous initiation of chemotherapy may resolve life-threatening pleural and pericardial effusions in cats with high-grade aberrant T-cell mediastinal lymphoma.

Suggested Citation

  • SJ Yu & HE Kim & HJ Han & JH Kim, 2022. "Successful management of feline CD4+ CD8+ T-cell mediastinal lymphoma with pericardial effusion," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 67(10), pages 544-551.
    • Handle: RePEc:caa:jnlvet:v:67:y:2022:i:10:id:70-2021-vetmed
    DOI: 10.17221/70/2021-VETMED
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