IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v66y2021i11id11-2021-vetmed.html
   My bibliography  Save this article

Clinical and immunohistochemical findings of splenic mast cell tumour in a cat: A case report

Author

Listed:
  • S Lee

    (Department of Veterinary Internal Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • MS Kang

    (Department of Anatomy, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • Y Jeong

    (Department of Veterinary Internal Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • Y Kim

    (Department of Veterinary Internal Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • HH Kwak

    (Department of Veterinary Surgery, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • EW Choi

    (Department of Veterinary Clinical Pathology, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • S Choi

    (Department of Veterinary Diagnostic Imaging, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea Seokwoo Lee and Min Soo Kang contributed equally to this work)

  • I Park

    (Department of Veterinary Diagnostic Imaging, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea Seokwoo Lee and Min Soo Kang contributed equally to this work)

  • JY Chung

    (Department of Veterinary Internal Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • JH Choi

    (Department of Anatomy, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

  • JO Ahn

    (Department of Veterinary Internal Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea)

Abstract

A 6-year-old, spayed, female, domestic shorthair cat presented with a 4-month history of chronic intermittent vomiting and anorexia. The haematologic results indicated moderate anaemia and a circulating mast cell population. The abdominal radiography revealed a markedly enlarged spleen. The cytological analysis of the spleen showed a uniform population of mast cells, and a diagnosis of systemic mastocytosis (splenic mast cell tumour with mastocytaemia) was made. This diagnosis was subsequently confirmed by the histopathological examination of the spleen. The immunohistochemistry for KIT showed KIT pattern II (focal cytoplasmic expression). A splenectomy and chemotherapy with vinblastine and prednisolone resulted in remission of the anaemia and other clinical signs. This case report highlights the importance of cytological evaluations of peripheral blood smears and/or aspirates of enlarged spleens for diagnosing splenic mast cell tumours and for quickly initiating the appropriate treatment.

Suggested Citation

  • S Lee & MS Kang & Y Jeong & Y Kim & HH Kwak & EW Choi & S Choi & I Park & JY Chung & JH Choi & JO Ahn, 2021. "Clinical and immunohistochemical findings of splenic mast cell tumour in a cat: A case report," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 66(11), pages 498-502.
    • Handle: RePEc:caa:jnlvet:v:66:y:2021:i:11:id:11-2021-vetmed
    DOI: 10.17221/11/2021-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/11/2021-VETMED.html
    Download Restriction: free of charge
    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/11/2021-VETMED.pdf
    Download Restriction: free of charge
    File URL: https://libkey.io/10.17221/11/2021-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:66:y:2021:i:11:id:11-2021-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.