IDEAS home Printed from https://ideas.repec.org/a/caa/jnlvet/v59y2014i2id7319-vetmed.html
   My bibliography  Save this article

Homozygous Pelger-Huet anomaly in three different crossbred rabbits: a case report

Author

Listed:
  • P. Supuka

    (University of Veterinary Medicine and Pharmacy, Kosice, Slovak Republic)

  • D. Mazensky

    (University of Veterinary Medicine and Pharmacy, Kosice, Slovak Republic)

  • A. Supukova

    (Pavol Jozef Safarik University, Faculty of Medicine, Kosice, Slovak Republic)

  • V. Parkanyi

    (Animal Production Research Centre Nitra, Luzianky, Slovak Republic)

  • L. Ondruska

    (Animal Production Research Centre Nitra, Luzianky, Slovak Republic)

  • S. Hornak

    (University of Veterinary Medicine and Pharmacy, Kosice, Slovak Republic)

  • R. Hromada

    (University of Veterinary Medicine and Pharmacy, Kosice, Slovak Republic)

  • V. Petrovic

    (University of Veterinary Medicine and Pharmacy, Kosice, Slovak Republic)

Abstract

In this case report, three different crossbreedings of pet rabbits were performed producing affected as well as healthy bunnies. All affected rabbits were smaller and had local alopecia, exophthalmus, and limb deviations compared to their healthy littermates; thus, a homozygous form of Pelger-Huet anomaly was suspected. This anomaly was confirmed by blood examination in which granulocytes with oval nuclei and a very coarse chromatin pattern, as well as lymphocytes with micronuclei were noticed. Karyotype analyses of the lymphocytes revealed many chromosomal aberrations in affected rabbits. Moreover, severe arterial abnormalities in the pelvic cavity and proximal part of the pelvic limbs were also found in these rabbits. Our findings suggest a multigenic origin of Pelger-Huet anomaly in rabbits, because only male and female offspring with the otter colour of fur were severely affected by this congenital disorder.

Suggested Citation

  • P. Supuka & D. Mazensky & A. Supukova & V. Parkanyi & L. Ondruska & S. Hornak & R. Hromada & V. Petrovic, 2014. "Homozygous Pelger-Huet anomaly in three different crossbred rabbits: a case report," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 59(2), pages 95-101.
    • Handle: RePEc:caa:jnlvet:v:59:y:2014:i:2:id:7319-vetmed
    DOI: 10.17221/7319-VETMED
    as

    Download full text from publisher

    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/7319-VETMED.html
    Download Restriction: free of charge
    File URL: http://vetmed.agriculturejournals.cz/doi/10.17221/7319-VETMED.pdf
    Download Restriction: free of charge
    File URL: https://libkey.io/10.17221/7319-VETMED?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:caa:jnlvet:v:59:y:2014:i:2:id:7319-vetmed. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Ivo Andrle (email available below). General contact details of provider: https://www.cazv.cz/en/home/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.