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Immunohistochemical localization of calbindin-D28k in the kidney and cerebellum of the porcupines (Hystrix cristata)

Author

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  • S. Timurkaan

    (, A. A 2, M. K 2 1Department of Histology-Embryology, 2Department of Anatomy, Faculty of Veterinary Medicine, University of Firat, Elazig, Turkey)

  • A. Aydin

    (, A. A 2, M. K 2 1Department of Histology-Embryology, 2Department of Anatomy, Faculty of Veterinary Medicine, University of Firat, Elazig, Turkey)

  • M. Kaban

    (, A. A 2, M. K 2 1Department of Histology-Embryology, 2Department of Anatomy, Faculty of Veterinary Medicine, University of Firat, Elazig, Turkey)

Abstract

The localization of calbindin in the kidney and cerebellum of Hystrix cristata was investigated immu­nohistochemically using an antiserum against the 28k Da calbindin of chicken duodenum. Calbindin-D28k is an intracellular protein with a high affinity for calcium. This protein is exclusively localized in the distal convoluted tubules of the kidney and in Purkinje cells of the cerebellum. Functionaly, calbindin-D28k is supposed to be involved in the regulation of the reabsorption of calcium in the distal nephron, though the exact regulatory mechanisms are not yet known.

Suggested Citation

  • S. Timurkaan & A. Aydin & M. Kaban, 2003. "Immunohistochemical localization of calbindin-D28k in the kidney and cerebellum of the porcupines (Hystrix cristata)," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 48(12), pages 369-372.
    • Handle: RePEc:caa:jnlvet:v:48:y:2003:i:12:id:5792-vetmed
    DOI: 10.17221/5792-VETMED
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    Cited by:

    1. A. Aydin & S. Yilmaz & G. Dinc & D. Ozdemir & M. Karan, 2005. "The morphology of circulus arteriosus cerebri in the porcupine (Hystrix cristata)," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 50(3), pages 131-135.

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